{"title":"Probiotic and microbiota engineering for practical applications","authors":"Tae Seok Moon","doi":"10.1016/j.cofs.2024.101130","DOIUrl":null,"url":null,"abstract":"<div><p>The last decades have witnessed amazing advances in engineering individual microbes for practical applications. However, engineering microbial consortia is a recent development, opening a new path for diverse applications, including curing gut diseases, solving food shortages, enabling sustainable bioproduction, mitigating pollution, and potentially addressing the climate crisis. In this perspective article, I will summarize recent technological innovations in synthetic biology that enable probiotic and microbiome engineering. Additionally, I will cover associated issues such as biosafety and biocontainment when the probiotics and microbiota are engineered. Given the complexity of global problems that are difficult to solve using a single microbe, this perspective will guide the research community to a better future with exciting potential applications.</p></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":null,"pages":null},"PeriodicalIF":8.9000,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Food Science","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214799324000080","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The last decades have witnessed amazing advances in engineering individual microbes for practical applications. However, engineering microbial consortia is a recent development, opening a new path for diverse applications, including curing gut diseases, solving food shortages, enabling sustainable bioproduction, mitigating pollution, and potentially addressing the climate crisis. In this perspective article, I will summarize recent technological innovations in synthetic biology that enable probiotic and microbiome engineering. Additionally, I will cover associated issues such as biosafety and biocontainment when the probiotics and microbiota are engineered. Given the complexity of global problems that are difficult to solve using a single microbe, this perspective will guide the research community to a better future with exciting potential applications.
期刊介绍：
Current Opinion in Food Science specifically provides expert views on current advances in food science in a clear and readable format. It also evaluates the most noteworthy papers from original publications, annotated by experts.
Key Features:
Expert Views on Current Advances: Clear and readable insights from experts in the field regarding current advances in food science.
Evaluation of Noteworthy Papers: Annotated evaluations of the most interesting papers from the extensive array of original publications.
Themed Sections: The subject of food science is divided into themed sections, each reviewed once a year.
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