Blood Oxygen Saturation Estimation with Laser-Induced Graphene Respiration Sensor

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Ana Madevska Bogdanova, Bojana Koteska, Teodora Vićentić, Stefan D. Ilić, Miona Tomić, Marko Spasenović
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Abstract

Measuring blood oxygen saturation (SpO2) is crucial in a triage process for identifying patients with respiratory distress or shock, since low SpO2 levels indicate compromised hemostability and the need for priority treatment. This paper explores the use of wearable mechanical deflection sensors based on laser-induced graphene (LIG) for SpO2 estimation. The LIG sensors are attached to a subject’s chest for real-time monitoring of respiratory signals. We have developed a novel database of the respiratory signals, with corresponding SpO2 values ranging from 86% to 100%. The database is used to develop an artificial neural network model for SpO2 estimation. The neural network performance is promising, with regression metrics mean squared error = 0.184, mean absolute error = 0.301, root mean squared error = 0.429, and R-squared = 0.804. The use of mechanical respiration sensors in combination with neural networks in biosensing opens new possibilities for noninvasive SpO2 monitoring and other innovative applications.
利用激光诱导石墨烯呼吸传感器估算血氧饱和度
测量血氧饱和度(SpO2)在分诊过程中对于识别呼吸窘迫或休克患者至关重要,因为低 SpO2 水平表明止血能力受损,需要优先治疗。本文探讨了如何使用基于激光诱导石墨烯(LIG)的可穿戴机械偏转传感器来估算 SpO2。LIG 传感器附着在受试者的胸部,用于实时监测呼吸信号。我们开发了一个新颖的呼吸信号数据库,其中包含从 86% 到 100% 的相应 SpO2 值。我们利用该数据库开发了一个人工神经网络模型,用于估算 SpO2。神经网络性能良好,回归指标均方误差 = 0.184,平均绝对误差 = 0.301,均方根误差 = 0.429,R 方 = 0.804。在生物传感中将机械呼吸传感器与神经网络结合使用,为无创 SpO2 监测和其他创新应用开辟了新的可能性。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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