{"title":"The Convergence of Graphene Quantum Dots and Peptides: Novel Strategy for Cellular Targeting in Cancer","authors":"Dilpreet Singh, Balak Das Kurmi, Amrinder Singh","doi":"10.2174/0115734137288288240108073034","DOIUrl":null,"url":null,"abstract":"In recent years, the convergence of two distinct nanomaterials, graphene quantum dots (GQDs) and peptides, has ushered in a new era of innovation in cancer therapeutics and biomedical research. GQDs, quasi-zero-dimensional graphene structures, have garnered significant attention due to their remarkable physicochemical properties, including excellent photoluminescence, high surface area, and biocompatibility [1]. Meanwhile, peptides, short amino acid sequences, have proven themselves as versatile molecular entities with a crucial role in cellular targeting, signaling, and communication. The convergence of these two domains, GQDs and peptides, has opened up exciting opportunities for developing novel nanocarriers and therapeutic platforms for the effective treatment of cancer [2]. The ligation of GQDs and peptides capitalizes on the unique properties of both components. GQDs exhibit exceptional optical properties, making them suitable for imaging and sensing applications [3]. Their high surface area allows for efficient drug loading, while their biocompatibility ensures minimal cytotoxicity. On the other hand, peptides offer molecular specificity, allowing for precise targeting of cancer cells and tissues. By combining these properties, GQD-peptide nanostructures can deliver therapeutic payloads to cancer sites with remarkable accuracy [4].","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Nanoscience","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.2174/0115734137288288240108073034","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
In recent years, the convergence of two distinct nanomaterials, graphene quantum dots (GQDs) and peptides, has ushered in a new era of innovation in cancer therapeutics and biomedical research. GQDs, quasi-zero-dimensional graphene structures, have garnered significant attention due to their remarkable physicochemical properties, including excellent photoluminescence, high surface area, and biocompatibility [1]. Meanwhile, peptides, short amino acid sequences, have proven themselves as versatile molecular entities with a crucial role in cellular targeting, signaling, and communication. The convergence of these two domains, GQDs and peptides, has opened up exciting opportunities for developing novel nanocarriers and therapeutic platforms for the effective treatment of cancer [2]. The ligation of GQDs and peptides capitalizes on the unique properties of both components. GQDs exhibit exceptional optical properties, making them suitable for imaging and sensing applications [3]. Their high surface area allows for efficient drug loading, while their biocompatibility ensures minimal cytotoxicity. On the other hand, peptides offer molecular specificity, allowing for precise targeting of cancer cells and tissues. By combining these properties, GQD-peptide nanostructures can deliver therapeutic payloads to cancer sites with remarkable accuracy [4].
期刊介绍:
Current Nanoscience publishes (a) Authoritative/Mini Reviews, and (b) Original Research and Highlights written by experts covering the most recent advances in nanoscience and nanotechnology. All aspects of the field are represented including nano-structures, nano-bubbles, nano-droplets and nanofluids. Applications of nanoscience in physics, material science, chemistry, synthesis, environmental science, electronics, biomedical nanotechnology, biomedical engineering, biotechnology, medicine and pharmaceuticals are also covered. The journal is essential to all researches involved in nanoscience and its applied and fundamental areas of science, chemistry, physics, material science, engineering and medicine.
Current Nanoscience also welcomes submissions on the following topics of Nanoscience and Nanotechnology:
Nanoelectronics and photonics
Advanced Nanomaterials
Nanofabrication and measurement
Nanobiotechnology and nanomedicine
Nanotechnology for energy
Sensors and actuator
Computational nanoscience and technology.