Heavy Metals in Blood Serum of Smokers and Non-smoking Controls

IF 1.7 4区化学 Q3 CHEMISTRY, ANALYTICAL

Current Analytical Chemistry Pub Date : 2024-01-29 DOI:10.2174/0115734110282582240116111759

Abdulhussein Abdulameer Alkufi, Mohanad Hussain Oleiwi, Ali Abid Abojassim

{"title":"Heavy Metals in Blood Serum of Smokers and Non-smoking Controls","authors":"Abdulhussein Abdulameer Alkufi, Mohanad Hussain Oleiwi, Ali Abid Abojassim","doi":"10.2174/0115734110282582240116111759","DOIUrl":null,"url":null,"abstract":"Background:: The analysis of heavy metals in the blood serum can serve as a reliable indicator for establishing the association between cigarette smoking and the presence of heavy metals Method:: In this study, performed in Al-Najaf during 2023, concentrations of three heavy metals - cadmium (Cd), chromium (Cr), and lead (Pb) – were investigated in two groups: cigarette smokers, and non-smokers (the control group) by using atomic absorption spectrophotometry (AAS). Participants in this experiment were categorized into five age groups: 21-30, 31-40, 41-50, 51-60, and 61- 70. Results:: The results showed that smokers displayed significantly higher blood serum concentrations of all heavy metals (Cd, Cr, and Pb) compared to non-smokers Furthermore, it is found that the mean concentrations of Cd, Cr, and Pb for smokers were 0.873±0.619 ppm, 1.957±0.883 ppm, and 0.043±0.021 ppm, respectively. For non-smokers, they were 0.197±0.165 ppm, 0.159±0.105 ppm, and 0.031±0.016 ppm, respectively. These differences were statistically significant. Overall, the mean heavy metal levels displayed a descending order in the present study, i.e. Cd > Cr > Pb.\" Conclusion:: The concentrations of Cd and Cr in all samples of the present study were higher than the biological limit according to ACGIH. Therefore, Cd and Cr were the most critical metals accumulated in the blood of cigarette smokers. Additionally, the findings have indicated that the analysis of blood serum samples can serve as a reliable indicator for establishing the association between cigarette smoking and the presence of heavy metals.","PeriodicalId":10742,"journal":{"name":"Current Analytical Chemistry","volume":"1 1","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Analytical Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.2174/0115734110282582240116111759","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}

引用次数: 0

Abstract

Background:: The analysis of heavy metals in the blood serum can serve as a reliable indicator for establishing the association between cigarette smoking and the presence of heavy metals Method:: In this study, performed in Al-Najaf during 2023, concentrations of three heavy metals - cadmium (Cd), chromium (Cr), and lead (Pb) – were investigated in two groups: cigarette smokers, and non-smokers (the control group) by using atomic absorption spectrophotometry (AAS). Participants in this experiment were categorized into five age groups: 21-30, 31-40, 41-50, 51-60, and 61- 70. Results:: The results showed that smokers displayed significantly higher blood serum concentrations of all heavy metals (Cd, Cr, and Pb) compared to non-smokers Furthermore, it is found that the mean concentrations of Cd, Cr, and Pb for smokers were 0.873±0.619 ppm, 1.957±0.883 ppm, and 0.043±0.021 ppm, respectively. For non-smokers, they were 0.197±0.165 ppm, 0.159±0.105 ppm, and 0.031±0.016 ppm, respectively. These differences were statistically significant. Overall, the mean heavy metal levels displayed a descending order in the present study, i.e. Cd > Cr > Pb." Conclusion:: The concentrations of Cd and Cr in all samples of the present study were higher than the biological limit according to ACGIH. Therefore, Cd and Cr were the most critical metals accumulated in the blood of cigarette smokers. Additionally, the findings have indicated that the analysis of blood serum samples can serve as a reliable indicator for establishing the association between cigarette smoking and the presence of heavy metals.

查看原文本刊更多论文

吸烟者和非吸烟对照组血清中的重金属含量

背景分析血清中的重金属可作为确定吸烟与重金属存在之间关系的可靠指标方法：本研究于 2023 年在 Al-Najaf 进行，采用原子吸收分光光度法 (AAS) 调查了两组吸烟者和非吸烟者（对照组）的镉 (Cd)、铬 (Cr) 和铅 (Pb) 三种重金属的浓度。实验参与者分为五个年龄组：21-30 岁、31-40 岁、41-50 岁、51-60 岁和 61-70 岁。实验结果吸烟者血清中所有重金属（镉、铬和铅）的平均浓度分别为 0.873±0.619 ppm、1.957±0.883 ppm 和 0.043±0.021 ppm。而非吸烟者则分别为 0.197±0.165 ppm、0.159±0.105 ppm 和 0.031±0.016 ppm。这些差异具有统计学意义。总体而言，本研究中重金属的平均水平呈降序排列，即镉 > 铬 > 铅"。结论：：本研究中所有样本的镉和铬浓度均高于 ACGIH 规定的生物限值。因此，镉和铬是吸烟者血液中积累的最重要的金属。此外，研究结果表明，血清样本分析可作为确定吸烟与重金属存在之间联系的可靠指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Analytical Chemistry 化学-分析化学

CiteScore

4.10

自引率

0.00%

发文量

审稿时长

9 months

期刊介绍： Current Analytical Chemistry publishes full-length/mini reviews and original research articles on the most recent advances in analytical chemistry. All aspects of the field are represented, including analytical methodology, techniques, and instrumentation in both fundamental and applied research topics of interest to the broad readership of the journal. Current Analytical Chemistry strives to serve as an authoritative source of information in analytical chemistry and in related applications such as biochemical analysis, pharmaceutical research, quantitative biological imaging, novel sensors, and nanotechnology.