Cost-effectiveness analysis of individual-level obesity treatment in paediatrics: A scoping review

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity Pub Date : 2024-01-29 DOI:10.1111/ijpo.13100

Ashwin Dhillon, Madeline Mayer, Lynn Kysh, D. Steven Fox, Elizabeth Hegedus, Alaina P. Vidmar

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引用次数: 0

Abstract

Objectives

This scoping review informs a health economics perspective on the treatment of paediatric obesity. The results detail recently published research findings on the cost-effectiveness of paediatric obesity treatments and identify key characteristics of cost-effective interventions.

Methods

A structured search was applied to six databases with no data restriction through March 2023: Medline, Embase, Cochrane CENTRAL, CINAHL, and PsycINFO. Studies that included a cost analysis of an individual level, weight management intervention (behavioural, pharmacotherapy, and surgical) in youth, with obesity, ages 2 to 21 years were eligible for inclusion.

Results

Of the 4371 records identified in the initial search, 353 underwent full-text review, 39 studies met the pre-specified inclusion criteria. The majority were published after 2010 (n = 36/39, 92%) and applied to high-income countries (n = 39/39, 100%). Thirty-five of the studies assessed the cost-effectiveness of lifestyle interventions (90%), and four studies assessed surgical outcomes (10%). No pharmacotherapy studies met eligibility criteria. Although the outcome measures differed across the studies, all four surgical interventions were reported to be cost-effective. Thirty of the 35 (85%) lifestyle modification studies were reported to be cost-effective compared to the study comparator examined.

Conclusions

There is a small amount of evidence that individual-level paediatric obesity treatment interventions are cost-effective and, in some cases cost-saving, with most of this work conducted on behavioural interventions. The economic evaluation of paediatric obesity interventions poses various methodologic challenges, which should be addressed in future research to fully use the potential of economic evaluation as an aid to decision-making.

查看原文本刊更多论文

儿科个人肥胖症治疗的成本效益分析：范围综述。

目的：本范围界定综述从卫生经济学的角度探讨了儿科肥胖症的治疗问题。研究结果详细介绍了近期发表的有关儿科肥胖症治疗成本效益的研究成果，并确定了具有成本效益的干预措施的主要特征：方法：在 2023 年 3 月之前，对六个无数据限制的数据库进行了结构化检索：Medline、Embase、Cochrane CENTRAL、CINAHL 和 PsycINFO。凡是对 2 至 21 岁青少年肥胖症患者的体重管理干预措施（行为疗法、药物疗法和手术疗法）进行成本分析的研究均符合纳入条件：在初步搜索出的 4371 条记录中，有 353 条进行了全文审阅，39 项研究符合预先规定的纳入标准。大部分研究发表于 2010 年之后（n = 36/39，92%），适用于高收入国家（n = 39/39，100%）。其中 35 项研究评估了生活方式干预的成本效益（90%），4 项研究评估了手术效果（10%）。没有符合资格标准的药物疗法研究。尽管各项研究的结果衡量标准有所不同，但所有四项手术干预措施均被报告为具有成本效益。据报道，在 35 项生活方式调整研究中，有 30 项（85%）与所审查的比较研究相比具有成本效益：有少量证据表明，个人层面的儿科肥胖症治疗干预措施具有成本效益，在某些情况下还能节省成本，其中大部分工作是针对行为干预措施开展的。对儿科肥胖症干预措施进行经济评估在方法上存在各种挑战，在未来的研究中应解决这些挑战，以充分利用经济评估的潜力作为决策的辅助工具。

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来源期刊

Pediatric Obesity PEDIATRICS-

CiteScore

7.30

自引率

5.30%

发文量

117

审稿时长

6-12 weeks

期刊介绍： Pediatric Obesity is a peer-reviewed, monthly journal devoted to research into obesity during childhood and adolescence. The topic is currently at the centre of intense interest in the scientific community, and is of increasing concern to health policy-makers and the public at large. Pediatric Obesity has established itself as the leading journal for high quality papers in this field, including, but not limited to, the following: Genetic, molecular, biochemical and physiological aspects of obesity – basic, applied and clinical studies relating to mechanisms of the development of obesity throughout the life course and the consequent effects of obesity on health outcomes Metabolic consequences of child and adolescent obesity Epidemiological and population-based studies of child and adolescent overweight and obesity Measurement and diagnostic issues in assessing child and adolescent adiposity, physical activity and nutrition Clinical management of children and adolescents with obesity including studies of treatment and prevention Co-morbidities linked to child and adolescent obesity – mechanisms, assessment, and treatment Life-cycle factors eg familial, intrauterine and developmental aspects of child and adolescent obesity Nutrition security and the "double burden" of obesity and malnutrition Health promotion strategies around the issues of obesity, nutrition and physical activity in children and adolescents Community and public health measures to prevent overweight and obesity in children and adolescents.