Proteasome Inhibitors in Multiple Myeloma

IF 2.5 3区 医学 Q2 HEMATOLOGY
Constantine S. Mitsiades MD, PhD
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引用次数: 0
蛋白酶体抑制剂在多发性骨髓瘤中的应用:功能基因组学对作用机制或抗药性的生物学启示。
在过去 20 年中,蛋白酶体抑制剂一直是治疗多发性骨髓瘤(MM)的基石。这篇综述重点介绍了随着时间的推移,多发性骨髓瘤的研究是如何发展的,其中包括我们对蛋白酶体抑制剂在多发性骨髓瘤中具有显著临床活性的机理基础的理解,以及该类药物在浆细胞异常以外的有限临床应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
86
审稿时长
6-12 weeks
期刊介绍: Hematology/Oncology Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced guest editor, each issue focuses on a single topic in hematology and oncology, including hemostasis and thrombosis, molecular and cellular basis of hematology, coagulation disorders, and cancers—bone, gastrointestinal, head and neck, lymphomas, neuroendocrine, breast, renal cell, melanoma, and more.
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