Management of late radiation tissue injury ulcers with continuous topical oxygen therapy supports wound healing in patients of advanced age following Mohs surgery: a case series.

IF 1.4 4区医学 Q3 DERMATOLOGY

Wounds : a compendium of clinical research and practice Pub Date : 2023-12-01

Windy Cole, Emma Woodmansey, Lawrence R LoDico Iii

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引用次数: 0

Abstract

Background: The long-term chronic effect of radiotherapy is commonly referred to as LRTI. Clinical complications such as skin atrophy, tissue fibrosis, endothelial damage, ulcer formation, and compromised wound healing are common sequela. Despite advances in medicine over the past decade, there remains a need for effective treatments for LRTI skin necrosis and ulcerations.

Materials and methods: This case series discusses cTOT in 3 patients of advanced age with LRTI wounds having undergone Mohs surgery. All wounds had been recalcitrant to multiple wound care treatments. All patients suffered with significant wound pain as well.

Results: cTOT resulted in complete wound healing in all 3 patient cases. Additionally, all 3 patients reported a significant reduction in wound pain during the course of therapy.

Conclusions: The positive outcomes exhibited in this case series suggest that cTOT is an effective treatment in the management of Mohs surgery patients with compromised wound healing due to radiation, advanced age, and comorbidities.

本刊更多论文

用持续的局部氧气疗法治疗晚期放射性组织损伤溃疡，支持莫氏手术后高龄患者的伤口愈合：病例系列。

背景：放疗的长期慢性效应通常被称为 LRTI。皮肤萎缩、组织纤维化、内皮损伤、溃疡形成和伤口愈合受阻等临床并发症是常见的后遗症。尽管过去十年来医学取得了进步，但仍需要对 LRTI 皮肤坏死和溃疡进行有效治疗：本系列病例讨论了 3 位接受过莫尔斯手术的 LRTI 伤口高龄患者的 cTOT。所有伤口均对多种伤口护理治疗无效。结果：3 例患者的 cTOT 均使伤口完全愈合。此外，在治疗过程中，所有 3 名患者的伤口疼痛都明显减轻：本系列病例所显示的积极结果表明，cTOT 是治疗因辐射、高龄和合并症而导致伤口愈合受损的莫氏手术患者的一种有效方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Wounds : a compendium of clinical research and practice 医学-皮肤病学

CiteScore

1.50

自引率

11.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Wounds is the most widely read, peer-reviewed journal focusing on wound care and wound research. The information disseminated to our readers includes valuable research and commentaries on tissue repair and regeneration, biology and biochemistry of wound healing, and clinical management of various wound etiologies. Our multidisciplinary readership consists of dermatologists, general surgeons, plastic surgeons, vascular surgeons, internal medicine/family practitioners, podiatrists, gerontologists, researchers in industry or academia (PhDs), orthopedic surgeons, infectious disease physicians, nurse practitioners, and physician assistants. These practitioners must be well equipped to deal with a myriad of chronic wound conditions affecting their patients including vascular disease, diabetes, obesity, dermatological disorders, and more. Whether dealing with a traumatic wound, a surgical or non-skin wound, a burn injury, or a diabetic foot ulcer, wound care professionals turn to Wounds for the latest in research and practice in this ever-growing field of medicine.