Endobronchial Tuberculosis in an HIV-positive Case.

IF 0.8 4区医学 Q4 IMMUNOLOGY

Current HIV Research Pub Date : 2024-01-01 DOI:10.2174/011570162X262663231214053029

Savaş Gegin, Burcu Özdemir, Özgür Günal, Şeyma Topal, Çiğdem Uzun, Levent Özdemir

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引用次数: 0

Abstract

Introduction: Tuberculosis is an opportunist infection that is fatal and most frequently seen in HIV-positive patients due to immunosuppression. Endobronchial lesions can portray symptoms in different ways. Endobronchial Tuberculosis is one of these lesions.

Case report: An HIV-positive, untreated 26-year-old patient with fever, cough, and dyspnea consulted our clinic. In the chest X-ray taken, effusion on the right side and non-homogeneous density increase in the middle and upper lobes, bilaterally more prominent on the right side, were observed. Therefore, the patient underwent bronchoscopy because the CT (computerized tomography) showed mediastinal lymphadenopathy (LAP) and an endobronchial lesion in the left main bronchus. During bronchoscopy, a vegetative endobronchial lesion that causes obstruction in the left main bronchus was monitored. With the help of Pathology and PCR results, endobronchial tuberculosis was diagnosed.

Conclusion: Even if Acid-alcohol-resistant Bacillus (ARB) is detected negative in patients who stop responding to antimicrobial treatment and are being monitored under radiological scanning, a distinctive diagnosis of endobronchial tuberculosis should be kept in mind while performing bronchoscopy.

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一例 HIV 阳性病例中的支气管内膜结核。

导言：结核病是一种致命的机会性感染，由于免疫抑制，最常见于艾滋病病毒阳性患者。支气管内病变可通过不同方式表现出症状。支气管内膜结核就是其中一种病变：病例报告：一名 26 岁的 HIV 阳性患者因发热、咳嗽和呼吸困难就诊于我院。在拍摄的胸部 X 光片中，发现右侧有渗出物，中叶和上叶有非均质密度增高，右侧更为突出。因此，患者接受了支气管镜检查，因为 CT（计算机断层扫描）显示纵隔淋巴结病（LAP）和左主支气管支气管内病变。在支气管镜检查过程中，监测到了导致左主支气管阻塞的支气管内植物性病变。在病理学和 PCR 结果的帮助下，确诊为支气管内膜结核：结论：即使抗酸杆菌（ARB）在对抗菌治疗停止反应并接受放射扫描监测的患者中检测为阴性，在进行支气管镜检查时仍应牢记支气管内膜结核的明确诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current HIV Research 医学-病毒学

CiteScore

1.90

自引率

10.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Current HIV Research covers all the latest and outstanding developments of HIV research by publishing original research, review articles and guest edited thematic issues. The novel pioneering work in the basic and clinical fields on all areas of HIV research covers: virus replication and gene expression, HIV assembly, virus-cell interaction, viral pathogenesis, epidemiology and transmission, anti-retroviral therapy and adherence, drug discovery, the latest developments in HIV/AIDS vaccines and animal models, mechanisms and interactions with AIDS related diseases, social and public health issues related to HIV disease, and prevention of viral infection. Periodically, the journal invites guest editors to devote an issue on a particular area of HIV research of great interest that increases our understanding of the virus and its complex interaction with the host.