A Case of Nasal Glial Heterotopia That Can Be Misdiagnosed as Storiform Patterned Sclerotic Fibroma/Collagenoma.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Fatma Gundogdu, Deniz Ates Ozdemir, Ibrahim Vargel
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引用次数: 0

Abstract

Objective: Nasal glioma, also known as nasal glial heterotopia, is a rare tumor-like lesion that often affects newborns or infants with no hereditary predisposition.

Case report: A 4-year-old child with a growth on the nasal dorsum since birth was diagnosed with nasal glial heterotopia/nasal glioma. The lesion showed a sclerotic fibroma/collagenoma-like storiform pattern with entrapped glial tissue that was S100 and GFAP positive.

Conclusion: When a biopsy of the nasal dorsum demonstrates sclerotic microscopic findings with a storiform pattern, nasal glioma should be considered before making a diagnosis in the collagen-rich tissue spectrum (collagenoma or Gardner's fibroma), and an immunohistochemical panel should be requested to demonstrate the presence of an unrecognized light microscopically visible glial component.

一例鼻腔胶质异位症,可误诊为星状花纹硬化性纤维瘤/胶原瘤。
摘要鼻胶质瘤又称鼻胶质异位症,是一种罕见的肿瘤样病变,通常发生在新生儿或婴儿身上,没有遗传倾向:病例报告:一名 4 岁儿童自出生起鼻背就长有赘生物,被诊断为鼻胶质异位症/鼻胶质瘤。病变呈硬化性纤维瘤/胶原瘤样星状形态,内含胶质组织,S100 和 GFAP 阳性:结论:当鼻背活组织检查显示硬化性显微镜检查结果并伴有storiform模式时,在做出富胶原组织谱(胶原瘤或Gardner纤维瘤)的诊断之前,应考虑鼻胶质瘤,并应要求进行免疫组化检查,以证明存在未被识别的光镜下可见的胶质成分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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