[A Case Report of Monkeypox Disease in an Adolescent].

IF 1.1 4区 医学 Q4 MICROBIOLOGY
Leyla Beşel, Önder Kılıçaslan, Çiğdem Kırmacı, Didem Kızmaz İsançlı, Irmak Emre, Adem Karbuz
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Abstract

Monkeypox virus (MPXV) infection is a zoonotic disease characterized by smallpox-like rashes. It is endemic in Central and West Africa. The World Health Organization (WHO) declared the disease as an epidemic due to a significant increase in the number of reported cases, starting from Europe and spreading to other regions, particularly in certain areas, in May 2022. On July 23, 2022, it was recognized as a public health problem of international importance. Our country has also been affected by this epidemic, and the official number of reported cases is twelve. In this case report, an adolescent case diagnosed with MPXV infection was presented. A 17-year-old male patient admitted with the complaints of sores around the mouth and genital area, fever and headache. The patient had a history of sexual contact with three different males in the last six months. Honey-colored crusted papules and plaques were observed in the perioral area, as well as crusted papules on the penile and gluteal areas. Ulcerative sores were present in the oral cavity. Laboratory tests for sexually transmitted diseases confirmed the patient's HIV-positive status and MPXV infection through PCR (polymerase chain reaction) testing. Antiviral treatment for human immunodeficiency virus (HIV) was initiated after the HIV RNA level resulted in 263000 copies/mL. Additionally, a glycopeptide was added to the treatment regimen when methicillin-resistant Staphylococcus aureus growth was detected in the swab culture taken from the wounds on the patient's face. No specific treatment was administered for MPXV due to the patient's uncomplicated clinical course and overall well-being. This case report aims to raise awareness about monkeypox disease in children by highlighting the clinical findings and potential risk factors.

[青少年猴痘病例报告]。
猴痘病毒(MPXV)感染是一种以类似天花的皮疹为特征的人畜共患疾病。它在非洲中部和西部流行。2022 年 5 月,由于报告病例数量显著增加,世界卫生组织(WHO)宣布该疾病为流行病。2022 年 7 月 23 日,该疾病被确认为具有国际重要性的公共卫生问题。我国也受到了这一流行病的影响,官方报告病例数为 12 例。本病例报告介绍了一例确诊感染 MPXV 的青少年病例。一名 17 岁的男性患者入院时主诉口腔和生殖器周围有溃疡、发烧和头痛。患者在过去 6 个月中曾与 3 名不同的男性有性接触史。口周出现蜜色结痂丘疹和斑块,阴茎和臀部也有结痂丘疹。口腔出现溃疡。通过聚合酶链反应(PCR)检测,性传播疾病实验室检测证实患者为艾滋病毒阳性和 MPXV 感染。在艾滋病毒 RNA 水平达到 263000 拷贝/毫升后,患者开始接受人类免疫缺陷病毒(HIV)抗病毒治疗。此外,当从患者面部伤口采集的拭子培养液中检测到耐甲氧西林金黄色葡萄球菌生长时,治疗方案中添加了糖肽。由于患者的临床病程并不复杂,整体状况良好,因此没有对 MPXV 进行特殊治疗。本病例报告旨在通过强调临床发现和潜在风险因素,提高人们对儿童猴痘疾病的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Mikrobiyoloji bulteni
Mikrobiyoloji bulteni 生物-微生物学
CiteScore
1.60
自引率
20.00%
发文量
50
审稿时长
6-12 weeks
期刊介绍: Bulletin of Microbiology is the scientific official publication of Ankara Microbiology Society. It is published quarterly in January, April, July and October. The aim of Bulletin of Microbiology is to publish high quality scientific research articles on the subjects of medical and clinical microbiology. In addition, review articles, short communications and reports, case reports, editorials, letters to editor and other training-oriented scientific materials are also accepted. Publishing language is Turkish with a comprehensive English abstract. The editorial policy of the journal is based on independent, unbiased, and double-blinded peer-review. Specialists of medical and/or clinical microbiology, infectious disease and public health, and clinicians and researchers who are training and interesting with those subjects, are the target groups of Bulletin of Microbiology.
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