Predictive Value of the Hb/RDW Ratio for the Risk of All-Cause Death in Patients with Heart Failure with Different Ejection Fractions.

IF 1.9 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Cardiology Pub Date : 2024-01-01 Epub Date: 2024-01-23 DOI:10.1159/000536440

Jing Zhou, Wenfang Ma, Yu Wan, Yanji Zhou, Wen Wan, Wenyi Gu, Hongxia Li, Chenggong Xu, Lixing Chen

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引用次数: 0

Abstract

Introduction: The prognostic value of the ratio of haemoglobin to red cell distribution width (HRR) in different types of heart failure (HF) is not well known.

Method and results: We analysed the long-term prognostic value of HRR in patients with HF using the Cox proportional risk model and Kaplan-Meier method. We reviewed consecutive 972 HF patients. The overall mortality rate was 45.68%. Mortality was 52.22% in the HFrEF group and 40.99% in the HFpEF + HFmrEF group. Cox regression showed that when HRR increased by 1 unit, the risk of all-cause death in all HF patients decreased by 22.8% (HR: 0.772, 95% CI: 0.724, 0.823, p < 0.001), in the HFpEF + HFmrEF group it decreased by 15.5% (HR: 0.845, 95% CI: 0.774, 0.923, p < 0.001), and in the HFrEF group it decreased by 36.1% (HR: 0.639, 95% CI: 0.576, 0.709, p < 0.0001). Subgroup analysis showed that there were interactions between the EF and HRR groups. The group in which HRR best predicted all-cause death from HF was group 1 (EF <40%, HRR <9.45), followed by group 2 (EF <40%, HRR ≥9.45), and group 3 (EF ≥40%, HRR <9.45). HRR had no predictive value in group 4 (EF ≥40%, HRR ≥9.45).

Conclusion: HRR is an important predictor of all-cause mortality in patients with HF, especially HFrEF. There is an interaction between HRR group and LVEF group.

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不同射血分数心衰患者 HB/RDW 比值对全因死亡风险的预测价值。

导言：不同类型心力衰竭（HF）患者血红蛋白与红细胞分布宽度比值（HRR）的预后价值尚不清楚：我们使用 Cox 比例风险模型和 Kaplan-Meier 法分析了 HRR 在心力衰竭患者中的长期预后价值。我们对连续 972 例高血压患者进行了复查。总死亡率为 45.68%。HFrEF组死亡率为52.22%，HFpEF+HFmrEF组死亡率为40.99%。Cox回归显示，当HRR增加1个单位时，所有HF患者的全因死亡风险降低了22.8%（HR：0.772，95% CI（0.724，0.823，p））：HRR是预测心房颤动患者（尤其是HFrEF）全因死亡率的重要指标。HRR组与LVEF组之间存在交互作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cardiology 医学-心血管系统

CiteScore

3.40

自引率

5.30%

发文量

审稿时长

1.5 months

期刊介绍： ''Cardiology'' features first reports on original clinical, preclinical and fundamental research as well as ''Novel Insights from Clinical Experience'' and topical comprehensive reviews in selected areas of cardiovascular disease. ''Editorial Comments'' provide a critical but positive evaluation of a recent article. Papers not only describe but offer critical appraisals of new developments in non-invasive and invasive diagnostic methods and in pharmacologic, nutritional and mechanical/surgical therapies. Readers are thus kept informed of current strategies in the prevention, recognition and treatment of heart disease. Special sections in a variety of subspecialty areas reinforce the journal''s value as a complete record of recent progress for all cardiologists, internists, cardiac surgeons, clinical physiologists, pharmacologists and professionals in other areas of medicine interested in current activity in cardiovascular diseases.