Strategies for Preventing Esophageal Stenosis After Endoscopic Submucosal Dissection and Progress in Stem Cell-Based Therapies.

IF 5.1 2区 医学 Q2 CELL & TISSUE ENGINEERING
Tissue Engineering. Part B, Reviews Pub Date : 2024-10-01 Epub Date: 2024-02-14 DOI:10.1089/ten.TEB.2023.0316
Shujun Ye, Jingjing Hu, Daxu Zhang, Shuo Zhao, Xiaonan Shi, Weilong Li, Jingyi Wang, Weiping Guan, Li Yan
{"title":"Strategies for Preventing Esophageal Stenosis After Endoscopic Submucosal Dissection and Progress in Stem Cell-Based Therapies.","authors":"Shujun Ye, Jingjing Hu, Daxu Zhang, Shuo Zhao, Xiaonan Shi, Weilong Li, Jingyi Wang, Weiping Guan, Li Yan","doi":"10.1089/ten.TEB.2023.0316","DOIUrl":null,"url":null,"abstract":"<p><p>Endoscopic submucosal dissection (ESD) has been widely used in the early neoplasia of the esophagus. However, postoperative esophageal stenosis is a big problem, particularly when a large circumferential proportion of esophageal mucosa is resected. Currently, there are several methods available to prevent esophageal stenosis after ESD, including steroid administration, esophageal stent implantation, and endoscopic balloon dilation (EBD). However, the therapeutic effects of these are not yet satisfactory. Stem cell-based therapies has shown promising potential in reconstructing tissue structure and restoring tissue function. In this study, we discussed the current strategies for preventing esophageal stenosis after ESD and perspectives of stem cell-based therapies for the prevention of esophageal stenosis.</p>","PeriodicalId":23134,"journal":{"name":"Tissue Engineering. Part B, Reviews","volume":null,"pages":null},"PeriodicalIF":5.1000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tissue Engineering. Part B, Reviews","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1089/ten.TEB.2023.0316","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/2/14 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CELL & TISSUE ENGINEERING","Score":null,"Total":0}
引用次数: 0

Abstract

Endoscopic submucosal dissection (ESD) has been widely used in the early neoplasia of the esophagus. However, postoperative esophageal stenosis is a big problem, particularly when a large circumferential proportion of esophageal mucosa is resected. Currently, there are several methods available to prevent esophageal stenosis after ESD, including steroid administration, esophageal stent implantation, and endoscopic balloon dilation (EBD). However, the therapeutic effects of these are not yet satisfactory. Stem cell-based therapies has shown promising potential in reconstructing tissue structure and restoring tissue function. In this study, we discussed the current strategies for preventing esophageal stenosis after ESD and perspectives of stem cell-based therapies for the prevention of esophageal stenosis.

预防 ESD 后食管狭窄的策略和干细胞疗法的进展。
内镜粘膜下剥离术(ESD)已被广泛应用于食管早期肿瘤的治疗。然而,术后食管狭窄是一个大问题,尤其是当切除的食管粘膜周缘比例较大时。目前,有几种方法可以预防 ESD 术后食管狭窄,包括类固醇用药、食管支架植入和内镜下球囊扩张(EBD)。然而,这些方法的治疗效果尚不令人满意。以干细胞为基础的疗法在重建组织结构和恢复组织功能方面具有广阔的前景。在此,我们讨论了目前预防ESD后食管狭窄的策略,以及干细胞疗法预防食管狭窄的前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Tissue Engineering. Part B, Reviews
Tissue Engineering. Part B, Reviews Biochemistry, Genetics and Molecular Biology-Biochemistry
CiteScore
12.80
自引率
1.60%
发文量
150
期刊介绍: Tissue Engineering Reviews (Part B) meets the urgent need for high-quality review articles by presenting critical literature overviews and systematic summaries of research within the field to assess the current standing and future directions within relevant areas and technologies. Part B publishes bi-monthly.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信