Linking telomere dynamics to evolution, life history and environmental change: perspectives, predictions and problems.

IF 4.4 4区医学 Q1 GERIATRICS & GERONTOLOGY

Biogerontology Pub Date : 2024-04-01 Epub Date: 2024-01-22 DOI:10.1007/s10522-023-10081-8

Pat Monaghan

引用次数: 0

Abstract

This perspectives paper considers the value of studying telomere biology outside of a biomedical context. I provide illustrative examples of the kinds of questions that evolutionary ecologists have addressed in studies of telomere dynamics in non-model species, primarily metazoan animals, and what this can contribute to our understanding of their evolution, life histories and health. I also discuss why the predicted relationships between telomere dynamics and life history traits, based on the detailed cellular studies in humans and model organisms, are not always found in studies in other species.

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将端粒动态与进化、生活史和环境变化联系起来：观点、预测和问题。

这篇视角论文探讨了在生物医学背景之外研究端粒生物学的价值。我举例说明了进化生态学家在研究非模式物种（主要是元祖类动物）端粒动态时所涉及的问题类型，以及这对我们理解它们的进化、生命史和健康有什么帮助。我还将讨论为什么在人类和模式生物的详细细胞研究基础上预测的端粒动态和生命史特征之间的关系并不总是能在其他物种的研究中找到。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biogerontology 医学-老年医学

CiteScore

8.00

自引率

4.40%

发文量

审稿时长

>12 weeks

期刊介绍： The journal Biogerontology offers a platform for research which aims primarily at achieving healthy old age accompanied by improved longevity. The focus is on efforts to understand, prevent, cure or minimize age-related impairments. Biogerontology provides a peer-reviewed forum for publishing original research data, new ideas and discussions on modulating the aging process by physical, chemical and biological means, including transgenic and knockout organisms; cell culture systems to develop new approaches and health care products for maintaining or recovering the lost biochemical functions; immunology, autoimmunity and infection in aging; vertebrates, invertebrates, micro-organisms and plants for experimental studies on genetic determinants of aging and longevity; biodemography and theoretical models linking aging and survival kinetics.