The uncharted territory of NAD⁺-capped RNA.

IF 13 1区生物学 Q1 CELL BIOLOGY

Trends in Cell Biology Pub Date : 2024-05-01 Epub Date: 2024-01-18 DOI:10.1016/j.tcb.2023.12.005

Quan Ma, Jianzhao Liu, Hao Hu, Zisheng Luo

引用次数: 0

Abstract

The critical redox cofactor NAD⁺ was recently reported to serve as an RNA cap in both eukaryotes and prokaryotes. However, its reversible regulation and biological functions remain unclear. Here, we provide insights into its discovery, capping and decapping mechanisms, for further discovery of their potential functional implications.

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NAD+ 封顶 RNA 的未知领域。

最近有报道称，在真核生物和原核生物中，关键氧化还原辅助因子 NAD+ 可作为 RNA 的帽。然而，它的可逆调节和生物功能仍不清楚。在此，我们将深入探讨其发现、加盖和脱盖机制，以进一步发现其潜在的功能意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in Cell Biology 生物-细胞生物学

CiteScore

32.00

自引率

0.50%

发文量

160

审稿时长

61 days

期刊介绍： Trends in Cell Biology stands as a prominent review journal in molecular and cell biology. Monthly review articles track the current breadth and depth of research in cell biology, reporting on emerging developments and integrating various methods, disciplines, and principles. Beyond Reviews, the journal features Opinion articles that follow trends, offer innovative ideas, and provide insights into the implications of new developments, suggesting future directions. All articles are commissioned from leading scientists and undergo rigorous peer-review to ensure balance and accuracy.

The uncharted territory of NAD+-capped RNA.

Abstract

The uncharted territory of NAD⁺-capped RNA.