Long-term changes in lung function after Roux-en-Y gastric bypass in patients with severe obesity

IF 2.2 Q3 ENDOCRINOLOGY & METABOLISM
Clinical Obesity Pub Date : 2024-01-18 DOI:10.1111/cob.12640
Kjetil Roth, Maria Støle, Ingvild Vadseth, Eivind Ottersen Samstad, Jorunn Sandvik, Dag Arne Lihaug Hoff
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Abstract

Obesity can decrease the lung function. The proposed mechanisms of reduced lung function in persons with obesity have been altered mechanical properties in the lung and chest wall, airway narrowing and increased respiratory resistance. The aim of this current study was to analyse the long-term results after gastric bypass surgery in patients with reduced lung function. The bariatric surgery observation study invited patients to a follow up 10 years after gastric bypass surgery. We compared the spirometry results before surgery to the spirometry 10 years after surgery. Thirty percent of 198 participants had reduced lung function before surgery. There was no significant relation between body mass index before surgery and lung function. Seventy-three percent of the participants with reduced lung function had normal lung function 10 years after surgery. There was no significant relation between the degree of weight loss and the improvement in lung function. Most participants with reduced lung function had normal lung function 10 years after gastric bypass surgery. There was no significant correlation between weight loss and improvement in lung function.

Abstract Image

重度肥胖症患者进行 Roux-en-Y 胃旁路术后肺功能的长期变化。
肥胖会降低肺功能。肥胖症患者肺功能下降的机制主要是肺和胸壁的机械特性改变、气道狭窄和呼吸阻力增加。本研究旨在分析肺功能减退患者接受胃旁路手术后的长期效果。减肥手术观察研究邀请患者在胃旁路手术后 10 年进行随访。我们将手术前的肺活量测定结果与手术 10 年后的肺活量测定结果进行了比较。在198名参与者中,有30%的人在手术前肺功能下降。手术前的体重指数与肺功能没有明显关系。在肺功能下降的参与者中,73%的人在术后10年肺功能正常。体重减轻程度与肺功能改善程度之间没有明显关系。大多数肺功能下降的参与者在胃旁路手术 10 年后肺功能恢复正常。体重减轻与肺功能改善之间没有明显关系。
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来源期刊
Clinical Obesity
Clinical Obesity ENDOCRINOLOGY & METABOLISM-
CiteScore
5.90
自引率
3.00%
发文量
59
期刊介绍: Clinical Obesity is an international peer-reviewed journal publishing high quality translational and clinical research papers and reviews focussing on obesity and its co-morbidities. Key areas of interest are: • Patient assessment, classification, diagnosis and prognosis • Drug treatments, clinical trials and supporting research • Bariatric surgery and follow-up issues • Surgical approaches to remove body fat • Pharmacological, dietary and behavioural approaches for weight loss • Clinical physiology • Clinically relevant epidemiology • Psychological aspects of obesity • Co-morbidities • Nursing and care of patients with obesity.
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