Derivation of the Extended Kawakita Equation for Estimating the Yield State of Powder in Die

IF 1.5 4区 医学 Q4 CHEMISTRY, MEDICINAL
Tsubasa Sato, Naoto Morita, Etsuo Yonemochi, Kozo Takayama
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Abstract

For powder compaction, the Kawakita equation has been used to estimate the powder behavior inside the die. The compression pressure exerted on powders is not homogeneous because of the friction on the die wall. However, the yield pressure and porosity estimated using the Kawakita equation are defined based on the assumption that homogeneous voids and compression pressure are distributed throughout the powder bed. In this study, an extended Kawakita equation was derived by considering the variation in the compression pressure as it corresponds to the distance from the loading punch surface. The yield time section estimated from the extended Kawakita equation was wider than that which was estimated via the classical equation. This result is consistent with the assumptions used to derive the extended Kawakita equation. Furthermore, a comparison of the porosity changes before and after the yield pressure was applied indicate that the direct cause of the yield is the spatial constraints of the powder particles. Equivalent stresses were defined to clarify the critical factor that constitutes the extended Kawakita equation. As a result, “taking into account the die wall friction” was considered to be the critical factor in the extended Kawakita equation. As these findings were theoretically determined by the extended Kawakita equation, a useful model was derived for a better understanding of powder compaction in die.

Abstract Image Fullsize Image
推导用于估算模具中粉末屈服状态的扩展川北方程
在粉末压制中,川北方程被用来估算粉末在模具内的行为。由于模具壁上的摩擦力,施加在粉末上的压缩压力并不均匀。然而,使用川北方程估算的屈服压力和孔隙率是基于均匀空隙和压缩压力分布于整个粉末床的假设来定义的。在本研究中,考虑到压缩压力的变化与距离加载冲头表面的距离相对应,推导出了扩展川北方程。根据扩展川北方程估算出的屈服时间截面比通过经典方程估算出的截面要宽。这一结果与推导扩展川北方程所使用的假设一致。此外,对施加屈服压力前后孔隙率变化的比较表明,屈服的直接原因是粉末颗粒的空间约束。通过定义等效应力,明确了构成扩展川北方程的关键因素。因此,"考虑模壁摩擦 "被认为是扩展川北方程的关键因素。由于这些结论是通过扩展川北方程从理论上确定的,因此得出了一个有用的模型,有助于更好地理解粉末在模具中的压实。
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来源期刊
CiteScore
3.20
自引率
5.90%
发文量
132
审稿时长
1.7 months
期刊介绍: The CPB covers various chemical topics in the pharmaceutical and health sciences fields dealing with biologically active compounds, natural products, and medicines, while BPB deals with a wide range of biological topics in the pharmaceutical and health sciences fields including scientific research from basic to clinical studies. For details of their respective scopes, please refer to the submission topic categories below. Topics: Organic chemistry In silico science Inorganic chemistry Pharmacognosy Health statistics Forensic science Biochemistry Pharmacology Pharmaceutical care and science Medicinal chemistry Analytical chemistry Physical pharmacy Natural product chemistry Toxicology Environmental science Molecular and cellular biology Biopharmacy and pharmacokinetics Pharmaceutical education Chemical biology Physical chemistry Pharmaceutical engineering Epidemiology Hygiene Regulatory science Immunology and microbiology Clinical pharmacy Miscellaneous.
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