Urinoids — a new tool to study bladder cancer

IF 12.1 1区医学 Q1 UROLOGY & NEPHROLOGY

Nature Reviews Urology Pub Date : 2024-01-16 DOI:10.1038/s41585-024-00853-3

Maria Chiara Masone

引用次数: 0

查看原文本刊更多论文

尿素--研究膀胱癌的新工具

目前治疗膀胱癌的方法仅对少数患者有效，这表明需要根据个体肿瘤特征进行个性化治疗。发表在《英国癌症杂志》（British Journal of Cancer）上的一项新研究利用患者的尿液（尿样组织）无创建立了膀胱癌有机体。这些尿样再现了原始肿瘤的组织学特征和遗传特征。此外，尿组织对膀胱癌疗法的反应与其组织器官类似物相似。尽管存在一些局限性，例如培养物感染的几率增加，但尿液组织是一种快速、无创的获取患者器官组织的方法，证明了连续监测患者肿瘤特征和治疗反应的可行性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nature Reviews Urology 医学-泌尿学与肾脏学

CiteScore

12.50

自引率

2.60%

发文量

123

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.