Comparison of the safety and efficacy of Neuroform Atlas stent deployed via Gateway balloon catheter and microcatheter for the treatment of intracranial stenosis

IF 3 3区医学 Q2 CLINICAL NEUROLOGY

Journal of Neuroradiology Pub Date : 2024-01-14 DOI:10.1016/j.neurad.2024.01.001

Deyuan Zhu , Dayong Qi , Wei Cao , Rongguo Hu, Kangqing Zhang, Tonghui Song, Peipei Ma, Tianheng Zheng, Yibin Fang

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引用次数: 0

Abstract

Objective

This study aimed to compare the safety and efficacy of the Atlas stent released by the Gateway catheter and microcatheter in the treatment of intracranial stenosis (IS).

Methods

The primary efficacy and safety outcomes were the in-stent restenosis (ISR) rate and post-procedural stroke or death within one month.

Results

Atlas stents were deployed using the Gateway catheter and microcatheter in 19 (57.6 %) and 14 (42.4 %) procedures, respectively. Follow-up imaging data were available for 26 patients; the incidence of ISR was 15.4 %, and the ISR rate was higher, though not significantly, in the microcatheter group than in the Gateway group (30.0% vs. 6.25 %, P = .39). Clinical follow-up data were available for 30 patients; the post-procedural stroke rate was 3.3 % within one month and 13.3 % from one month to one year. The post-procedural stroke rate within one month was higher, though not significantly, in the microcatheter group than in the Gateway group (7.7% vs. 0 %, P = .43). The Gateway group had a significantly lower rate of post-procedural stroke in the same territory than that of the microcatheter group (0% vs. 30.8 %, P = .026). A higher incidence of residual stenosis <30 % was found in the non-ISR group than in the ISR group (72.2% vs. 0 %, P = .014).

Conclusions

This study provides preliminary evidence that the Atlas stent is safe and effective for IS treatment. The use of the Gateway catheter to deliver the Atlas stent appears to be safer than using microcatheter. The incidence of ISR may be related to the degree of the residual stenosis.

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通过Gateway球囊导管和微导管部署Neuroform Atlas支架治疗颅内狭窄的安全性和有效性比较

方法主要疗效和安全性结果是支架内再狭窄（ISR）率和术后一个月内中风或死亡。结果在19例（57.6%）和14例（42.4%）手术中分别使用Gateway导管和微导管置入了Atlas支架。26名患者获得了随访影像数据；ISR发生率为15.4%，微导管组的ISR发生率高于Gateway组，但差异不显著（30.0% vs. 6.25%，P=.39）。有 30 名患者的临床随访数据；术后一个月内中风率为 3.3%，一个月至一年内中风率为 13.3%。微导管组的术后一个月内中风率高于 Gateway 组（7.7% 对 0%，P=.43），但差异不明显。Gateway 组术后同一区域中风的发生率明显低于微导管组（0% vs. 30.8%，P=.026）。非 ISR 组残余狭窄率 <30% 的发生率高于 ISR 组（72.2% 对 0%，P=.014）。使用Gateway导管置入Atlas支架似乎比使用微导管更安全。ISR的发生率可能与残余狭窄的程度有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Neuroradiology 医学-核医学

CiteScore

6.10

自引率

5.70%

发文量

142

审稿时长

6-12 weeks

期刊介绍： The Journal of Neuroradiology is a peer-reviewed journal, publishing worldwide clinical and basic research in the field of diagnostic and Interventional neuroradiology, translational and molecular neuroimaging, and artificial intelligence in neuroradiology. The Journal of Neuroradiology considers for publication articles, reviews, technical notes and letters to the editors (correspondence section), provided that the methodology and scientific content are of high quality, and that the results will have substantial clinical impact and/or physiological importance.