Pregnancy with Systemic Lupus Erythematosus with Sjogren Syndrome and intrauterine fetal heart block: A successful pregnancy outcome: A case report:

Naima Sharmin Hoque, A T M Tanvir, Nurun Nahar Fatema, Mohammad Shakhawat Alam, Shariful Islam Seraji
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Abstract

Fertility is not impaired with autoimmune diseases. Pregnant women with autoimmune diseases, are likely toexperience more complications than are women without the disease. Pregnancies complicated by these disordershave a high clinical impact on both the pregnancy and the disease. Sjögren syndrome is an autoimmune disease witha high prevalence of anti-SS-A (anti-Ro) and anti-SS-B (anti-La) antibodies. Anti-SS-A antibodies are associatedwith congenital heart block. Women with Primary Sjögren syndrome require prenatal counseling explaining the risksinvolved and the need to control the disease well before conception. High-risk pregnancies can be optimally managedby a multidisciplinary team. Excessive fetal morbidity and mortality have been noted in patients with systemic lupuserythematosus (SLE). The influence of anti-SSA/Ro antibodies on fetal outcome in SLE patients has rarely beenreported, but its high association with congenital heart block or neonatal lupus syndrome is well known. Here we arepresenting a case Mrs. Tahiya, 34 years, 2nd gravida with 37+wks pregnancy with SLE with Sjogren Syndrome withuncontrolled DM with history of previous 1 LSCS. This case was managed in multidisciplinary approach.
妊娠合并系统性红斑狼疮和 Sjogren 综合征及胎儿宫内心脏传导阻滞:成功的妊娠结局:病例报告:
自身免疫性疾病不会影响生育能力。患有自身免疫性疾病的孕妇可能会比没有这种疾病的孕妇经历更多的并发症。妊娠并发症对妊娠和疾病都有很大的临床影响。斯约格伦综合征是一种自身免疫性疾病,抗-SS-A(抗-Ro)和抗-SS-B(抗-La)抗体的发病率很高。抗SS-A抗体与先天性心脏传导阻滞有关。患有原发性斯约恩综合征的妇女需要接受产前咨询,解释其中的风险以及在受孕前控制疾病的必要性。高危妊娠可由多学科团队进行最佳管理。系统性红斑狼疮(SLE)患者的胎儿发病率和死亡率都很高。抗SSA/Ro抗体对系统性红斑狼疮患者胎儿预后的影响鲜有报道,但其与先天性心脏传导阻滞或新生儿狼疮综合征的高度相关性却是众所周知的。在此,我们介绍一例 Tahiya 女士,34 岁,第二次怀孕,妊娠 37 周以上,患有系统性红斑狼疮和 Sjogren 综合征,糖尿病未得到控制,既往有 1 次 LSCS 病史。该病例采用多学科方法进行治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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