Impact of Polycystic Ovary Syndrome on Periodontal Status of Women of Adolescent and Adult Age Groups: A Cross-Sectional Study.

IF 2.9 3区医学 Q1 MEDICINE, GENERAL & INTERNAL

Medical Principles and Practice Pub Date : 2024-01-01 Epub Date: 2024-01-11 DOI:10.1159/000536223

Swati Jaglan, Shikha Tewari, Savita Rani Singhal, Rajinder Kumar Sharma

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Abstract

Objective: Polycystic ovary syndrome (PCOS) is identified as the most common endocrine disorder in reproductive-aged women, and symptoms of PCOS appear during the early pubertal age. There is a gap in knowledge in recognizing the status of gingival inflammation/periodontal destruction and high-sensitivity C-reactive protein levels (hsCRP) in adolescents versus adults with PCOS. This study aimed to observe the impact of PCOS on periodontal status and systemic inflammation in adolescents and compared them with adults with PCOS.

Methods: A total of 100 newly diagnosed female subjects with PCOS were enrolled into two groups: adolescents (11-19 years, n = 50) and adult females (20-40 years, n = 50). Periodontal parameters, anthropometric parameters, PCOS phenotype, hirsutism score, and serum hsCRP levels were recorded.

Results: High levels of mean hsCRP, gingival index, and bleeding on probing % were observed in adolescent and adult PCOS groups, though nonsignificant between the groups (p > 0.05). Significantly more sites with probing pocket depth 3-4 mm, higher mean clinical attachment level (CAL) and sites with CAL 1-2 mm, and high frequency of patients (n = 11) with periodontitis (stage 1) were observed in adults with PCOS compared to adolescents (p ≤ 0.05). Similar and predominant prevalence of PCOS phenotype A (66%) and moderate hirsutism (46% adolescents vs. 58% adults) were observed in both groups.

Conclusion: Similar levels of hsCRP and periodontal inflammation were found in adolescents and adults with PCOS. More periodontal tissue destruction was observed in adults with PCOS as compared to adolescents with PCOS.

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多囊卵巢综合征对青少年和成年女性牙周状况的影响：一项横断面研究

目的：多囊卵巢综合征（PCOS多囊卵巢综合征（PCOS）是育龄妇女最常见的内分泌疾病，其症状在青春期早期就会出现。在认识患有多囊卵巢综合征的青少年与成年人的牙龈炎症/牙周破坏状况和高敏C反应蛋白水平（hsCRP）方面存在知识空白。本研究旨在观察多囊卵巢综合征对青少年牙周状况和全身炎症的影响，并与患有多囊卵巢综合征的成年人进行比较：方法：共招募了 100 名新确诊的多囊卵巢综合征女性受试者，分为两组：青少年（11 - 19 岁，n = 50）和成年女性（20 - 40 岁，n = 50）。记录了牙周参数、人体测量参数、多囊卵巢综合征表型、多毛症评分和血清 hsCRP 水平：结果：在青少年组和成年多囊卵巢综合征组观察到高水平的平均 hsCRP、GI 和 BOP%，但组间差异不显著（P > 0.05）。与青少年相比，成人多囊卵巢综合征患者中 PPD 3 - 4 mm 的部位明显增多，平均 CAL 和 CAL 1 - 2 mm 的部位较高，牙周炎（1 期）患者（n = 11）的频率也较高（p ≤ 0.05）。两组患者的多囊卵巢综合征表型 A（66%）和中度多毛症（46% 的青少年和 58% 的成年人）发病率相似且占主导地位：结论：青少年和成人多囊卵巢综合征患者的 hsCRP 和牙周炎症水平相似。结论：在患有多囊卵巢综合征的青少年和成年人中，发现了相似水平的 hsCRP 和牙周炎症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medical Principles and Practice 医学-医学：内科

CiteScore

6.10

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： ''Medical Principles and Practice'', as the journal of the Health Sciences Centre, Kuwait University, aims to be a publication of international repute that will be a medium for dissemination and exchange of scientific knowledge in the health sciences.