Randomized trial in rural Native American homes heated with wood stoves: results from the EldersAIR study

IF 2.9 4区 环境科学与生态学 Q3 ENVIRONMENTAL SCIENCES
Curtis W. Noonan, Ethan S. Walker, Erin O. Semmens, Annie Belcourt, Johna Boulafentis, Crissy Garcia, Jon Graham, Nolan Hoskie, Eugenia Quintana, Julie Simpson, Paul Smith, Howard L. Teasley Jr, Desirae Ware, Emily Weiler, Tony J. Ward
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Abstract

Residential wood burning has both practical and traditional values among many indigenous communities of the US Mountain West, although household biomass burning also results in emissions that are harmful to health. In a household-level three-arm placebo-controlled randomized trial, we tested the efficacy of portable filtration units and education interventions on improving pulmonary function and blood pressure measures among elder participants that use wood stoves for residential heating. A total of 143 participants were assigned to the Education (n = 49), Filter (n = 47), and Control (n = 47) arms. Blood pressure and spirometry measures were collected multiple times during a pre-intervention winter period and during a follow-up post-intervention winter period. Despite strong PM2.5 exposure reduction results with the Filter arm (50% lower compared to Control arm), neither this intervention nor the Education intervention translated to improvements in the selected health measures among this population with a mixture of chronic conditions. Intention to treat analysis failed to demonstrate evidence that either of the intervention arms had beneficial effects on the blood pressure or the spirometry measures. Post hoc evaluation of effect modification for blood pressure and spirometry outcomes did not reveal any interaction influence on the outcomes according to sex, residential smoking, chronic disease history, and study area.

ClinicalTrials.gov: NCT02240069.

Abstract Image

Abstract Image

在使用木柴炉取暖的美国农村原住民家中进行的随机试验:EldersAIR 研究的结果
在美国西部山区的许多原住民社区中,住宅烧柴既实用又具有传统价值,但家用生物质燃烧也会产生有害健康的废气。在一项家庭层面的三臂安慰剂对照随机试验中,我们测试了便携式过滤装置和教育干预对改善使用木柴炉取暖的老年参与者的肺功能和血压指标的效果。共有 143 名参与者被分配到教育组(49 人)、过滤组(47 人)和对照组(47 人)。在干预前的冬季和干预后的冬季随访期间,多次收集血压和肺活量测量数据。尽管过滤组的PM2.5暴露量减少效果显著(与对照组相比减少了50%),但这一干预措施和教育干预措施都没有改善这一混合慢性病人群的选定健康指标。治疗意向分析未能证明干预措施对血压或肺活量测量产生了有利影响。对血压和肺活量结果的效应修正进行的事后评估没有发现性别、居住地吸烟情况、慢性病史和研究地区对结果有任何交互影响:NCT02240069。
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来源期刊
Air Quality Atmosphere and Health
Air Quality Atmosphere and Health ENVIRONMENTAL SCIENCES-
CiteScore
8.80
自引率
2.00%
发文量
146
审稿时长
>12 weeks
期刊介绍: Air Quality, Atmosphere, and Health is a multidisciplinary journal which, by its very name, illustrates the broad range of work it publishes and which focuses on atmospheric consequences of human activities and their implications for human and ecological health. It offers research papers, critical literature reviews and commentaries, as well as special issues devoted to topical subjects or themes. International in scope, the journal presents papers that inform and stimulate a global readership, as the topic addressed are global in their import. Consequently, we do not encourage submission of papers involving local data that relate to local problems. Unless they demonstrate wide applicability, these are better submitted to national or regional journals. Air Quality, Atmosphere & Health addresses such topics as acid precipitation; airborne particulate matter; air quality monitoring and management; exposure assessment; risk assessment; indoor air quality; atmospheric chemistry; atmospheric modeling and prediction; air pollution climatology; climate change and air quality; air pollution measurement; atmospheric impact assessment; forest-fire emissions; atmospheric science; greenhouse gases; health and ecological effects; clean air technology; regional and global change and satellite measurements. This journal benefits a diverse audience of researchers, public health officials and policy makers addressing problems that call for solutions based in evidence from atmospheric and exposure assessment scientists, epidemiologists, and risk assessors. Publication in the journal affords the opportunity to reach beyond defined disciplinary niches to this broader readership.
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