Peak-aware adaptive denoising for Raman spectroscopy based on machine learning approach

Abstract

Raman spectroscopy can be effectively used for detection and analysis of chemical agents that are serious threats in modern warfare, but the detection and analysis performance is prone to deterioration due to noise. The existing denoising technique has limitations that there is no criterion for selecting the window length and that the filtering distorts the peaks, key features for Raman spectral data analysis. To overcome such limitations, in this paper, we propose the peak-aware adaptive denoising for Raman spectroscopy based on machine learning approach. The proposed technique utilizes the information of detected peaks to eliminate noise effectively using different window values optimal for each region in the Raman spectrum while preserving the shape of peaks. We conducted the various analyses and experiments, and the proposed technique showed a 28% lower Euclidean distance and a 48% lower Fréchet inception distance compared to the existing technique, meaning the proposed technique outperformed the existing one.