Brewing wellness: sugar-based synthesis of anti-obesity celastrol

IF 14 2区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Trends in Chemistry Pub Date : 2024-01-09 DOI:10.1016/j.trechm.2023.12.006

Yi Lou, Yifeng Huang, Jiangtao Gao

引用次数: 0

Abstract

Addressing the burgeoning global obesity crisis, Zhao et al. recently presented innovative developments in celastrol synthesis, a potent anti-obesity agent. They unified plant biochemistry, metabolic engineering, and chemistry to map an effective celastrol biosynthetic path in yeast. The study emphasizes new opportunities for the commercial production of celastrol, revealing future potential for specialized metabolite production.

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酿造健康：以糖为基础合成抗肥胖青霉烯醇

为了应对日益严重的全球肥胖危机，Zhao 等人最近介绍了一种有效的抗肥胖药物--青霉酚合成的创新发展。他们将植物生物化学、代谢工程和化学相结合，在酵母中绘制了一条有效的青霉酚生物合成路径。该研究强调了青霉烯醇商业化生产的新机遇，揭示了特殊代谢物生产的未来潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in Chemistry CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

28.00

自引率

0.60%

发文量

138

期刊介绍： Trends in Chemistry serves as a new global platform for discussing significant and transformative concepts across all areas of chemistry. It recognizes that breakthroughs in chemistry hold the key to addressing major global challenges. The journal offers readable, multidisciplinary articles, including reviews, opinions, and short pieces, designed to keep both students and leading scientists updated on pressing issues in the field. Covering analytical, inorganic, organic, physical, and theoretical chemistry, the journal highlights major themes such as biochemistry, catalysis, environmental chemistry, materials, medicine, polymers, and supramolecular chemistry. It also welcomes articles on chemical education, health and safety, policy and public relations, and ethics and law.