Converting heterotrophic Saccharomyces cerevisiae to a synthetic methylotroph

IF 14 2区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Trends in Chemistry Pub Date : 2024-01-10 DOI:10.1016/j.trechm.2023.12.004

Pan Zhu, Ziqi Zhang, Yufei Li

引用次数: 0

Abstract

It is challenging to convert a non-methylotrophic yeast to a synthetic methylotroph. In a recently described new method, Nielsen, Keasling, Chen, Bai, and coworkers show that Saccharomyces cerevisiae can be engineered to grow solely on methanol, which potentially emerges as a promising platform for one-carbon (C1)-based biomanufacturing.

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将异养型酿酒酵母转化为合成甲基营养体

将非养甲型酵母转化为合成的养甲型酵母具有挑战性。在最近描述的一种新方法中，Nielsen、Keasling、Chen、Bai 及其同事表明，可以改造酿酒酵母菌，使其只在甲醇中生长，这有可能成为基于一碳（C1）的生物制造的一个前景广阔的平台。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in Chemistry CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

28.00

自引率

0.60%

发文量

138

期刊介绍： Trends in Chemistry serves as a new global platform for discussing significant and transformative concepts across all areas of chemistry. It recognizes that breakthroughs in chemistry hold the key to addressing major global challenges. The journal offers readable, multidisciplinary articles, including reviews, opinions, and short pieces, designed to keep both students and leading scientists updated on pressing issues in the field. Covering analytical, inorganic, organic, physical, and theoretical chemistry, the journal highlights major themes such as biochemistry, catalysis, environmental chemistry, materials, medicine, polymers, and supramolecular chemistry. It also welcomes articles on chemical education, health and safety, policy and public relations, and ethics and law.