Entire Papilla Preservation Technique with Recombinant Human Fibroblast Growth Factor-2 and Autogenous Bone Grafting in the Treatment of Isolated, Noncontained Intrabony Defects: Case Report with a 5-Year Follow-up.

Abstract

Regenerative periodontal surgery is an effective procedure for the treatment of intrabony defects. Various flap designs that preserve defect-associated interdental papillae have been proposed to improve early wound stability. This case report describes the long-term results of a regenerative treatment in a severely compromised mandibular canine using the entire papilla preservation technique. Surgical access was provided by a single buccal vertical incision without any papilla incision. A combination of autogenous bone harvested from the same surgical site and recombinant human fibroblast growth factor-2 was applied to a noncontained intrabony defect following the removal of granulation tissue. The surgical site was closed with single interrupted sutures. The clinical outcomes after 5 years showed stable pocket closure without any increase in gingival recession, highlighting the potential of the entire papilla preservation technique with the use of combined biomaterials.