Impact of Clonal Heterogeneity in Multiple Myeloma

IF 2.5 3区医学 Q2 HEMATOLOGY

Hematology-Oncology Clinics of North America Pub Date : 2024-01-08 DOI:10.1016/j.hoc.2023.12.012

Carolina Schinke MD , Leo Rasche MD , Marc S. Raab MD , Niels Weinhold PhD

引用次数: 0

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多发性骨髓瘤克隆异质性的影响

多发性骨髓瘤的特点是疾病在含骨髓的骨骼系统中分布高度异质性。在这篇综述中，我们介绍了克隆异质性的分子机制以及骨髓瘤的时空演变。我们讨论了克隆异质性的临床影响，它被认为是克服耐药性和实现治愈的最大障碍之一。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Hematology-Oncology Clinics of North America 医学-血液学

CiteScore

4.10

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Hematology/Oncology Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced guest editor, each issue focuses on a single topic in hematology and oncology, including hemostasis and thrombosis, molecular and cellular basis of hematology, coagulation disorders, and cancers—bone, gastrointestinal, head and neck, lymphomas, neuroendocrine, breast, renal cell, melanoma, and more.