HbA1c and risk factors' prevalence in patients with stroke: a retrospective study in a tertiary care hospital in Saudi Arabia.

IF 1.2 4区医学 Q4 CLINICAL NEUROLOGY

Neurosciences Pub Date : 2024-01-01 DOI:10.17712/nsj.2024.1.20230037

Faisal K Alfakeeh, Yazeed M Alghamdi, Bassam F Alharbi, Abdulaziz M Alotaibi, Khalid A Alsaleh, Abdullah M Alshubaili, Ryan H Mcrabi, Farhan K Alenazi, Awad Almuklass

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引用次数: 0

Abstract

Objectives: To determine the relationship between hemoglobin A1c (HbA1c) and different types of stroke, and how different comorbidities and risk factors are related to the occurrence of stroke in a Saudi Arabian tertiary care hospital.

Methods: This retrospective study was conducted at King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia. The study included patients who experienced either hemorrhagic stroke (HS), ischemic stroke (IS), or transient ischemic attack (TIA) between 2015 and 2020.

Results: In total, 976 patients were included, of whom 670 were males (68.6%). The incidence of HS was significantly higher in males compared to females (14.2% vs. 6.9%), whereas the incidence of IS was higher in females (76.8% vs. 74.6%) (p=0.001). Ischemic stroke was significantly higher in the 65 years or older age group, whereas HS was comparatively higher among those aged <65 years. The means HbA1c levels in all three types of stroke were abnormally high. However, HbA1c levels were significantly higher in IS than in the other 2 stroke types (p=0.017). The HbA1c levels showed statistically significant differences between the different types of stroke, where the estimated marginal means were higher in patients with IS with a small effect size. Heart disease was also more prevalent in the IS group. Stroke-related mortality was reported in 16 patients and was significantly higher in the IS group than in the HS group.

Conclusion: The HbA1c levels were elevated in all types of stroke, significantly in IS. Controlling patients' HbA1c and other modifiable risk factors could significantly reduce the risk of stroke.

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中风患者的 HbA1c 和风险因素流行率：沙特阿拉伯一家三级医院的回顾性研究。

目的确定血红蛋白 A1c（HbA1c）与不同类型中风之间的关系，以及不同合并症和风险因素与沙特阿拉伯一家三级医院中风发生的关系：这项回顾性研究在沙特阿拉伯王国利雅得的阿卜杜勒-阿齐兹国王医疗城进行。研究对象包括 2015 年至 2020 年期间发生出血性中风（HS）、缺血性中风（IS）或短暂性脑缺血发作（TIA）的患者：共纳入 976 名患者，其中 670 人为男性（68.6%）。男性 HS 发病率明显高于女性（14.2% 对 6.9%），而女性 IS 发病率较高（76.8% 对 74.6%）（P=0.001）。缺血性中风的发病率在 65 岁或以上年龄组中明显较高，而 HS 的发病率在 65 岁或以上年龄组中相对较高，P=0.017）。不同类型中风的 HbA1c 水平在统计学上有显著差异，其中 IS 患者的估计边际均值较高，但影响较小。心脏病在 IS 组中的发病率也较高。据报道，有16名患者出现了与中风相关的死亡，IS组的死亡率明显高于HS组：结论：各种类型的中风患者 HbA1c 水平均升高，IS 组患者的 HbA1c 水平明显升高。控制患者的 HbA1c 和其他可改变的风险因素可显著降低中风风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurosciences 医学-临床神经学

CiteScore

1.40

自引率

0.00%

发文量

审稿时长

4.5 months

期刊介绍： Neurosciences is an open access, peer-reviewed, quarterly publication. Authors are invited to submit for publication articles reporting original work related to the nervous system, e.g., neurology, neurophysiology, neuroradiology, neurosurgery, neurorehabilitation, neurooncology, neuropsychiatry, and neurogenetics, etc. Basic research withclear clinical implications will also be considered. Review articles of current interest and high standard are welcomed for consideration. Prospective workshould not be backdated. There are also sections for Case Reports, Brief Communication, Correspondence, and medical news items. To promote continuous education, training, and learning, we include Clinical Images and MCQ’s. Highlights of international and regional meetings of interest, and specialized supplements will also be considered. All submissions must conform to the Uniform Requirements.