Postoperative Dipping Patterns of Mean Arterial Pressure and Mortality After Coronary Artery Bypass Grafting.

IF 2.4 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Cardiovascular Translational Research Pub Date : 2024-04-01 Epub Date: 2024-01-09 DOI:10.1007/s12265-023-10475-6

Bohao Jian, Haoliang Liu, Yi Zhang, Gang Li, Song Yang, Guangguo Fu, Suiqing Huang, Yang Huang, Zhuoming Zhou, Zhongkai Wu, Mengya Liang

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Abstract

Blood pressure dipping patterns have long been considered to be associated with adverse events. We aimed to investigate whether dipping patterns of postoperative MAP were related to 90-day and hospital mortality in patients undergoing CABG. Four thousand three hundred ninety-one patients were classified into extreme dippers (night-to-day ratio of MAP ≤ 0.8), dippers (0.8 < night-to-day ratio of MAP ≤ 0.9), non-dippers (0.9 < night-to-day ratio of MAP ≤ 1), and reverse dippers (> 1). Compared with non-dippers, reverse dippers were at a higher risk of 90-day mortality (aHR = 1.58; 95% CI, 1.10-2.27) and hospital mortality (aOR = 1.97; 95% CI, 1.12-3.47). A significant interaction was observed between hypertension and dipping patterns (P for interaction = 0.02), with a significant increased risk of 90-day mortality in non-hypertensive reverse dippers (aHR = 1.90; 95% CI, 1.17-3.07) but not in hypertensive reverse dippers (aHR = 1.26; 95% CI, 0.73-2.19).

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冠状动脉旁路移植术后平均动脉压下降模式与死亡率。

血压下降模式一直被认为与不良事件有关。我们的目的是研究接受 CABG 手术的患者术后 MAP 的骤降模式是否与 90 天死亡率和住院死亡率有关。我们将四千三百九十一名患者分为极度骤降者（MAP 夜比≤0.8）、骤降者（0.8 1）和反向骤降者（0.8 1）。与非降压者相比，反向降压者的 90 天死亡率（aHR = 1.58；95% CI，1.10-2.27）和住院死亡率（aOR = 1.97；95% CI，1.12-3.47）风险更高。高血压与滂沱模式之间存在明显的交互作用（交互作用的 P = 0.02），非高血压反向滂沱者 90 天死亡风险明显增加（aHR = 1.90；95% CI，1.17-3.07），但高血压反向滂沱者没有增加（aHR = 1.26；95% CI，0.73-2.19）。

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来源期刊

Journal of Cardiovascular Translational Research CARDIAC & CARDIOVASCULAR SYSTEMS-MEDICINE, RESEARCH & EXPERIMENTAL

CiteScore

6.10

自引率

2.90%

发文量

148

审稿时长

6-12 weeks

期刊介绍： Journal of Cardiovascular Translational Research (JCTR) is a premier journal in cardiovascular translational research. JCTR is the journal of choice for authors seeking the broadest audience for emerging technologies, therapies and diagnostics, pre-clinical research, and first-in-man clinical trials. JCTR''s intent is to provide a forum for critical evaluation of the novel cardiovascular science, to showcase important and clinically relevant aspects of the new research, as well as to discuss the impediments that may need to be overcome during the translation to patient care.