Postoperative Dipping Patterns of Mean Arterial Pressure and Mortality After Coronary Artery Bypass Grafting.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2024-04-01 Epub Date: 2024-01-09 DOI:10.1007/s12265-023-10475-6

Bohao Jian, Haoliang Liu, Yi Zhang, Gang Li, Song Yang, Guangguo Fu, Suiqing Huang, Yang Huang, Zhuoming Zhou, Zhongkai Wu, Mengya Liang

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Abstract

Blood pressure dipping patterns have long been considered to be associated with adverse events. We aimed to investigate whether dipping patterns of postoperative MAP were related to 90-day and hospital mortality in patients undergoing CABG. Four thousand three hundred ninety-one patients were classified into extreme dippers (night-to-day ratio of MAP ≤ 0.8), dippers (0.8 < night-to-day ratio of MAP ≤ 0.9), non-dippers (0.9 < night-to-day ratio of MAP ≤ 1), and reverse dippers (> 1). Compared with non-dippers, reverse dippers were at a higher risk of 90-day mortality (aHR = 1.58; 95% CI, 1.10-2.27) and hospital mortality (aOR = 1.97; 95% CI, 1.12-3.47). A significant interaction was observed between hypertension and dipping patterns (P for interaction = 0.02), with a significant increased risk of 90-day mortality in non-hypertensive reverse dippers (aHR = 1.90; 95% CI, 1.17-3.07) but not in hypertensive reverse dippers (aHR = 1.26; 95% CI, 0.73-2.19).

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冠状动脉旁路移植术后平均动脉压下降模式与死亡率。

血压下降模式一直被认为与不良事件有关。我们的目的是研究接受 CABG 手术的患者术后 MAP 的骤降模式是否与 90 天死亡率和住院死亡率有关。我们将四千三百九十一名患者分为极度骤降者（MAP 夜比≤0.8）、骤降者（0.8 1）和反向骤降者（0.8 1）。与非降压者相比，反向降压者的 90 天死亡率（aHR = 1.58；95% CI，1.10-2.27）和住院死亡率（aOR = 1.97；95% CI，1.12-3.47）风险更高。高血压与滂沱模式之间存在明显的交互作用（交互作用的 P = 0.02），非高血压反向滂沱者 90 天死亡风险明显增加（aHR = 1.90；95% CI，1.17-3.07），但高血压反向滂沱者没有增加（aHR = 1.26；95% CI，0.73-2.19）。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464