Arcuate Nucleus of the Hypothalamus: Anatomy, Physiology, and Diseases.

IF 1.8 4区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Experimental Neurobiology Pub Date : 2023-12-31 DOI:10.5607/en23040

Juhyun Song, Seok-Yong Choi

引用次数: 0

Abstract

The hypothalamus is part of the diencephalon and has several nuclei, one of which is the arcuate nucleus. The arcuate nucleus of hypothalamus (ARH) consists of neuroendocrine neurons and centrally-projecting neurons. The ARH is the center where the homeostasis of nutrition/metabolism and reproduction are maintained. As such, dysfunction of the ARH can lead to disorders of nutrition/metabolism and reproduction. Here, we review various types of neurons in the ARH and several genetic disorders caused by mutations in the ARH.

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下丘脑弓状核：解剖学、生理学和疾病。

下丘脑是双脑的一部分，有几个核，其中之一是弓状核。下丘脑弓状核（ARH）由神经内分泌神经元和中枢投射神经元组成。下丘脑弓状核是维持营养/代谢和生殖平衡的中枢。因此，ARH 的功能障碍可导致营养/代谢和生殖失调。在此，我们回顾了 ARH 中的各类神经元以及 ARH 基因突变导致的几种遗传疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Experimental Neurobiology Neuroscience-Cellular and Molecular Neuroscience

CiteScore

4.30

自引率

4.20%

发文量

期刊介绍： Experimental Neurobiology is an international forum for interdisciplinary investigations of the nervous system. The journal aims to publish papers that present novel observations in all fields of neuroscience, encompassing cellular & molecular neuroscience, development/differentiation/plasticity, neurobiology of disease, systems/cognitive/behavioral neuroscience, drug development & industrial application, brain-machine interface, methodologies/tools, and clinical neuroscience. It should be of interest to a broad scientific audience working on the biochemical, molecular biological, cell biological, pharmacological, physiological, psychophysical, clinical, anatomical, cognitive, and biotechnological aspects of neuroscience. The journal publishes both original research articles and review articles. Experimental Neurobiology is an open access, peer-reviewed online journal. The journal is published jointly by The Korean Society for Brain and Neural Sciences & The Korean Society for Neurodegenerative Disease.