Xin-Xin Feng , Lei Chen , Yong-Yi Xu , Kai Zhou , Kai-Yu Huang
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引用次数: 0
Abstract
Introduction
The hazard of Parkinson's disease-related constipation (PDC) cannot be ignored. Acupuncture has the potential to become a mainstream treatment option for PDC. This review aimed to investigate the effect of acupuncture on PDC, which might provide evidence-based recommendations for clinical application.
Methods
Six databases were searched for randomized controlled trials (RCTs) about acupuncture for PDC. The primary outcome was response rate. The secondary outcomes were rectal resting pressure, anal resting pressure, anal maximum contraction pressure, rectal sensation threshold, rectal maximum tolerable volume, the Constipation Scoring System (CSS) score, the Patient Assessment of Constipation Quality of Life (PAC-QOL) score, and adverse events (AEs).
Results
Eight trials involving 591 participants were included. The methodological quality was generally low. A significant difference was found in response rate when comparing acupuncture with medicine (95 %CI= 1.09 to 1.54, P = 0.003) or blank control (95 %CI= 1.04 to 1.74, P = 0.02), while no significant difference was observed when comparing acupuncture + medicine with medicine. Acupuncture + medicine did have a significant effect on rectal resting pressure, anal resting pressure, anal maximum contraction pressure, rectal sensation threshold and rectal maximum tolerable volume when compared with medicine, while no significant effect was found when acupuncture was compared with medicine. A significant difference was found in the CSS score when acupuncture was compared with blank and in the PAC-QOL score when acupuncture was compared with sham or blank, while no significant difference was found in the PAC-QOL score when acupuncture was compared with medicine. One study reported mild AEs.
Conclusions
Acupuncture might be an effective treatment for PDC. Due to the limited quality of evidence, high-caliber and multi-center RCTs with large sample sizes should be carried out.
期刊介绍：
The European Journal of Integrative Medicine (EuJIM) considers manuscripts from a wide range of complementary and integrative health care disciplines, with a particular focus on whole systems approaches, public health, self management and traditional medical systems. The journal strives to connect conventional medicine and evidence based complementary medicine. We encourage submissions reporting research with relevance for integrative clinical practice and interprofessional education.
EuJIM aims to be of interest to both conventional and integrative audiences, including healthcare practitioners, researchers, health care organisations, educationalists, and all those who seek objective and critical information on integrative medicine. To achieve this aim EuJIM provides an innovative international and interdisciplinary platform linking researchers and clinicians.
The journal focuses primarily on original research articles including systematic reviews, randomized controlled trials, other clinical studies, qualitative, observational and epidemiological studies. In addition we welcome short reviews, opinion articles and contributions relating to health services and policy, health economics and psychology.
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