Efficacy of 3D-printed customized titanium implants and its clinical validation in foot and ankle surgery

IF 6.8 3区医学 Q1 ENGINEERING, BIOMEDICAL

International Journal of Bioprinting Pub Date : 2023-07-24 DOI:10.36922/ijb.0125

Yangjing Lin, P. He, Guangyu Yang, Fuyou Wang, L. Jia, Huaquan Fan, Liu Yang, Huiping Tang, Xiaojun Duan

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引用次数: 0

Abstract

In foot and ankle surgery, internal fixation was crucial to maintain the stability of bony structure, and bone grafting material is commonly used to treat bone defects. With rapid development of three-dimensional (3D) printing technology, new advances were made in these two aspects. In this study, digital image correlation method (DICM) data of the patient’s ankle via computed tomography (CT) examination were obtained and imported into a series of software. The engineer cooperated with the surgeon to design the customized implants. Ti-6Al-4V spherical metal powder was chosen as raw material and fused together by selective electron beam melting (SEBM), a type of 3D printing technology, to prepare the implant. The implants were sterilized with ethylene oxide. The customized 3D-printed implants were successfully utilized in tibiotalocalcaneal (TTC) arthrodesis to maintain the bony structures at the functional position. In another case, the 3D-printed fusion cage was applied in subtalar arthrodesis to treat bone defects. In these clinical cases, 3D-printed customized titanium implants helped improve the surgical operation flow, and no obvious tissue reaction was observed. The successful implementation suggested that the application of 3D printing technology to prepare customized titanium implants would play an important role in future foot and ankle surgery.

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3D 打印定制钛植入物在足踝手术中的功效及其临床验证

在足踝外科手术中，内固定是保持骨结构稳定的关键，而骨移植材料则常用于治疗骨缺损。随着三维打印技术的快速发展，这两方面都取得了新的进展。本研究通过计算机断层扫描（CT）获取了患者踝关节的数字图像关联法（DICM）数据，并将其导入一系列软件。工程师与外科医生合作设计了定制植入物。选用 Ti-6Al-4V 球形金属粉末作为原材料，并通过选择性电子束熔化（SEMM）（一种三维打印技术）将其融合在一起，制备植入体。植入体用环氧乙烷灭菌。定制的三维打印植入物被成功用于胫骨-腓骨-踝骨（TTC）关节成形术，将骨性结构保持在功能位置。在另一个病例中，三维打印融合笼被应用于距骨下关节成形术，以治疗骨缺损。在这些临床病例中，3D打印定制钛植入物有助于改善手术操作流程，且未观察到明显的组织反应。这些案例的成功实施表明，应用 3D 打印技术制备定制钛植入物将在未来的足踝外科手术中发挥重要作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Bioprinting Multiple-

CiteScore

6.90

自引率

4.80%

发文量

期刊介绍： The International Journal of Bioprinting is a globally recognized publication that focuses on the advancements, scientific discoveries, and practical implementations of Bioprinting. Bioprinting, in simple terms, involves the utilization of 3D printing technology and materials that contain living cells or biological components to fabricate tissues or other biotechnological products. Our journal encompasses interdisciplinary research that spans across technology, science, and clinical applications within the expansive realm of Bioprinting.