DEPRESSIVE DISORDERS AND PROGNOSIS IN PATIENTS WITH ISCHEMIA-INDUCED CHRONIC HEART FAILURE

Violetta M. Iakubova, Olga V. Bulashova, Elena V. Khazova
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Abstract

Abstract. Introduction. Clinical depression occurs in 21.5% of patients with heart failure, aggravating both the clinical course and the prognosis of the disease. The aim is to present the findings of the clinical course of chronic heart failure in patients with depressive disorders and to study their prognoses. Material and Methods. The study included 78 patients with heart failure, functional classes 1-4. The degree of depressive disorders was assessed using the Hospital Anxiety and Depression Scale (HADS). Life quality was assessed using the Minnesota Living with Heart Failure Questionnaire. All patients passed a 6-minute walk test and echocardiography. The patient’s clinical condition was assessed according to the clinical condition assessment scale. Prognoses were assessed after 1 year of study. Results and Discussion. Depression level analysis has shown that the clinically pronounced depression is common in patients with heart failure, which corresponds to 9.0 (6.0;11.0) points. In a closer consideration of the structure of disorders, no depression was found in 37.2 % of cases, subclinical depression was found less frequently in patients with heart failure (26.9 %), while clinical depression was found in 35.9 %. All-cause mortality was observed in 7.7 % of cases, while cardiovascular mortality occurred in 4.6 %. Pronounced depression was registered in patients with chronic heart failure, in case of hospital admission. Conclusions. Average depression level in patients with heart failure is 9.0 (6.0; 11.0) points, which corresponds with clinical depression. Depression occurs in 62.8 % of cases and associated with worse clinical condition. Overt clinical depression occurs more frequently in patients with chronic heart failure, who have come up to the event of hospitalization.
缺血诱发慢性心力衰竭患者的抑郁障碍和预后
摘要。导言。21.5%的心力衰竭患者患有临床抑郁症,这会加重疾病的临床过程和预后。本文旨在介绍抑郁症患者慢性心力衰竭的临床病程,并研究其预后。材料与方法研究对象包括 78 名功能分级为 1-4 级的心力衰竭患者。采用医院焦虑抑郁量表(HADS)评估抑郁障碍程度。生活质量采用明尼苏达心衰患者生活问卷进行评估。所有患者均通过了 6 分钟步行测试和超声心动图检查。患者的临床状况根据临床状况评估量表进行评估。研究一年后对预后进行评估。结果与讨论抑郁程度分析表明,临床上明显的抑郁在心衰患者中很常见,相当于 9.0(6.0;11.0)分。仔细观察病症的结构,37.2%的病例未发现抑郁症,亚临床抑郁症在心衰患者中的发现率较低(26.9%),而临床抑郁症的发现率为 35.9%。全因死亡率为 7.7%,心血管死亡率为 4.6%。慢性心力衰竭患者在入院时会明显感到抑郁。结论心力衰竭患者的平均抑郁程度为 9.0 (6.0; 11.0) 分,与临床抑郁相符。62.8%的病例出现抑郁,并与临床状况恶化有关。慢性心力衰竭患者在住院治疗时更容易出现明显的临床抑郁。
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