Clinical Factors Associated With Extreme Sleep Apnea in Patients Living at High Altitude (Bogotá D.C., Colombia): A Case–Control Study

Q3 Medicine

Revista Colombiana de Psiquiatria Pub Date : 2025-03-01 DOI:10.1016/j.rcp.2023.10.002

Franklin Escobar-Córdoba , Jorge Rey de Castro , Charles Huamaní

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引用次数: 0

Abstract

Objective

To assess risk factors associated with extreme obstructive sleep apnea (OSA) in patients living at high altitudes.

Methods

A case–control study was conducted using data collected between 2016 and 2017 in patients who lived in Bogotá D.C. (2640 m above sea level) and were treated at FUNDASUVICOL. Participants: Six hundred twenty patients met the inclusion criteria: 110 had moderate OSA, 144 had severe OSA, 203 had very severe OSA and 163 had extreme OSA (cases). The controls–cases ratio was 3:1. Measurements: Participants’ data were obtained from their medical records. Logistic regression models were used to calculate adjusted odds ratios and 95% confidence intervals.

Results

The bivariate analysis showed that the following variables were associated with extreme OSA: morbid obesity (ORcrude = 32.22; 95% CI = 9.10–114.1), high blood pressure (HBP) (ORcrude = 2.40; 95% CI = 1.66–3.46), snoring (ORcrude = 4.69; 95% CI = 1.42–15.45), body mass index (BMI) (ORcrude = 1.14; 95% CI = 1.10–1.18), neck circumference (ORcrude = 1.13; 95% CI = 1.08–1.18) and age (ORcrude = 1.02; 95% CI = 1.01–1.04). Somehow, after performing a multivariate regression analysis adjusted by age, gender, morbid obesity, snoring, HBP and neck circumference, it was determined that only morbid obesity (OR = 8.34; 95% CI = 2.04–34.05) and neck circumference (OR = 1.09; 95% CI = 1.01–1.16) are risk factors for extreme OSA.

Discussion

Morbid obesity and neck circumference were significantly associated with extreme OSA. Therefore, losing weight and improving anthropometric measurements should be considered in OSA treatment to reduce the severity of symptoms and to improve polysomnographic parameters in these patients.

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来源期刊

Revista Colombiana de Psiquiatria Medicine-Psychiatry and Mental Health

CiteScore

2.50

自引率

0.00%

发文量

期刊介绍： Revista Colombiana de Psiquiatría (RCP) is a quarterly official publication of Colombian Psychiatry Association (March, June, September and December) and its purpose is to spread different the knowledge models that currently constitute the theoretical and practical body of our specialty. Psychiatrists, psychiatric residents, non psychiatric physicians, psychologists, philosophers or other health professionals or persons interested in this area can take part in the magazine. This journal publishes original works, revision or updating articles, case reports of all psychiatry and mental health areas, epistemology, mind philosophy, bioethics and also articles about methodology of investigation and critical reading.