Treatment and management of rheumatoidarthritis

Hari Krishna K, Meghana B, Mercia Rani G, Anitha K, Jagadeesh A, Jalaiah M
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Abstract

Rheumatoid arthritis is an autoimmune inflammatory disease characterized mostly by synovitis, which is frequently Clinical manifestations include fever, malaise, edema, pain, and stiffness in several joints are followed with extra-articular organ involvement, such as interstitial pneumonia. After the initial stage, joint degradation progresses swiftly, and once the afflicted areas' deformed joints are obvious, physical dysfunction that cannot be reversed begins to occur. Thus, precise diagnosis and Treatment is required from the moment the problem first appears. While anti-inflammatory drugs and glucocorticoids were used as palliative care, disease-modifying anti-rheumatic drugs (DMARDs) are currently used to slow down and control the advancement of sickness and immunological diseases. By maintaining remission, these drugs have also been shown to halt the advancement of joint degradation and physical disability over a prolonged period of time. Precision medicine, safer and more effective treatment techniques targeted at drug holidays or cures, and therapeutic strategies are some of the future developments in medicine.
类风湿关节炎的治疗和管理
类风湿性关节炎是一种自身免疫性炎症性疾病,以滑膜炎为主要特征,临床表现为多个关节发热、不适、水肿、疼痛和僵硬,随后出现关节外器官受累,如间质性肺炎。在初期阶段之后,关节退化进展迅速,一旦患病部位关节变形明显,就会出现无法逆转的身体功能障碍。因此,从问题出现的那一刻起,就需要进行精确的诊断和治疗。过去,抗炎药和糖皮质激素被用作姑息治疗,而现在,改变病情的抗风湿药(DMARDs)被用来延缓和控制疾病和免疫性疾病的发展。通过维持病情缓解,这些药物还被证明可以长期阻止关节退化和身体残疾的发展。精准医疗、针对药物假期或治愈的更安全、更有效的治疗技术以及治疗策略是未来医学的一些发展方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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