Evaluation of osteopathic treatment effectiveness in patients with upper thoracic aperture syndrome

Irina A. Egorova, Artem V. Dyupin, Roman S. Danisko, A. Chervotok
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Abstract

Background. Upper thoracic aperture syndrome occurs in 2–8% of people in the population and affects patients of the most working age, mainly women. Aim. Evaluation of the combined (drug + osteopathic) treatment effectiveness of patients with upper thoracic aperture syndrome compared to drug therapy. Material and methods. In a randomized study, patients with signs of upper thoracic aperture syndrome were divided into two groups: the main group received combined (osteopathic + drug) treatment for 2 months; the control group received only drug treatment (non-steroidal anti-inflammatory drugs, muscle relaxants, thioctic acid preparations) for 2 months. Each group consisted of 15 women aged from 25 to 47 years (main group — 36.31±7.33 years, control group — 35.18±6.76 years), the duration of the disease ranged from 6 to 18 months (main group — 12.02±3.57 months, control group — 11.07±3.97 months). The groups were comparable in age composition and duration of the disease. To assess the effectiveness of the treatment, the dynamics of symptoms of neuropathic pain, stimulation electroneuromyography, and the dynamics of osteopathic status indicators were used. Data were presented as arithmetic mean and standard deviation. When analyzing intergroup differences, the nonparametric Mann–Whitney test (U-test), and when analyzing intragroup differences, the nonparametric Wilcoxon test (W-test) were used. The statistical significance of the difference in the frequency of osteopathic dysfunctions and other frequency parameters before and after treatment was assessed using the Pearson χ2 test. The critical level of statistical significance was taken as 5% (p=0.05). Results. The combination of osteopathic and drug treatment led to a difference in conduction along the right ulnar nerve between groups (p=0.0003) in the main group — an increase in speed from 48.1±1.54 m/s to 61.0±3.34 m/s (p=0.0007), in the control group — from 46.8±1.89 m/s to 50.2±4.85 m/s (p=0.0009). Analysis of the NTTSS-9 scale (assessment of symptoms of neuropathic pain) after treatment showed no difference between the groups (p=0.0941): the main group — before treatment 14±2.14 points, after treatment 2±1.4 points (p =0.0003), control group — before treatment 15±1.95 points, after treatment 6±2.80 points (p=0.0007). Conclusion. In the group that received combined (osteopathic + drug treatment), a greater increase in conductivity along the ulnar nerve was found.
上胸廓开孔综合征患者的整骨疗法疗效评估
背景。上胸廓开孔综合征的发病率为 2%-8%,患者多为工作年龄段的人,以女性为主。 目的与药物治疗相比,评估上胸廓开孔综合征患者的联合(药物+整骨疗法)治疗效果。 材料和方法。在随机研究中,将有上胸廓开孔综合征体征的患者分为两组:主治组接受为期 2 个月的联合(整骨疗法 + 药物)治疗;对照组仅接受为期 2 个月的药物治疗(非甾体抗炎药、肌肉松弛剂、硫辛酸制剂)。每组 15 名妇女,年龄在 25 至 47 岁之间(主要组--36.31±7.33 岁,对照组--35.18±6.76 岁),病程在 6 至 18 个月之间(主要组--12.02±3.57 个月,对照组--11.07±3.97 个月)。两组患者的年龄构成和病程具有可比性。为评估治疗效果,采用了神经病理性疼痛症状动态、刺激电神经肌电图和骨病状态指标动态。数据以算术平均数和标准差表示。分析组间差异时,采用非参数曼-惠特尼检验(U 检验);分析组内差异时,采用非参数威尔科克森检验(W 检验)。使用 Pearson χ2 检验评估治疗前后骨科功能障碍频率和其他频率参数差异的统计学意义。统计显著性临界水平为 5%(P=0.05)。 结果整骨疗法和药物治疗相结合,导致右尺神经的传导速度在组间出现差异(P=0.0003),主要组从 48.1±1.54 m/s 增加到 61.0±3.34 m/s (P=0.0007),对照组从 46.8±1.89 m/s 增加到 50.2±4.85 m/s (P=0.0009)。治疗后的 NTTSS-9 量表(神经病理性疼痛症状评估)分析表明,各组之间无差异(p=0.0941):主治组--治疗前为 14±2.14 分,治疗后为 2±1.4 分(p=0.0003);对照组--治疗前为 15±1.95 分,治疗后为 6±2.80 分(p=0.0007)。 结论在接受联合治疗(整骨疗法+药物治疗)的组中,发现尺神经的传导性有了更大的提高。
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