Diyabetik Ayak Olan ve Olmayan Diabetes Mellitus Hastalarında Kuru Göz Bulgularının Karşılaştırılması

Gülce GÖKGÖZ ÖZIŞIK, Hasan Çakmak, Murat Kendi̇rci̇, Osman Dağ
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Abstract

Purpose: To compare dry eye findings in diabetes mellitus patients with and without diabetic foot. Methods: Diabetes mellitus patients with and without diabetic foot were included in this controlled cross-sectional study. Tear break-up time (BUT) and Schirmer test results of each participant were noted. Ocular Surface Disease Index (OSDI) questionnaire was administered to each participant. Results: There were 48 diabetic patients in the study; half of them had diabetic foot (n=24). The patients with and without diabetic foot were similar in age and sex distribution. The median levels of BUT (4.0 [3.0 – 6.0] seconds for the right eye, 4.5 [3.0 – 6.5] seconds for the left eye in patients with diabetic foot) (4.0 [3.8 – 6.2] seconds for the right eye, 5.0 [3.8 – 5.2] second for the left eye in patients without diabetic foot) and Schirmer’s test (7.0 [5.0 – 17.0] mm for the right eye, 11.0 [6.8 – 17.0] mm for the left eye in patients with diabetic foot) (11.0 [7.0 – 15.8] mm for the right eye, 14.5 [6.5 – 18.5] mm for the left eye in patients without diabetic foot) were similar in both groups of patients. The scores of OSDI were similar in patients with diabetic foot (22.7 [13.5 – 36.2]) and without diabetic foot (28.4 [13.6 – 41.5]) (p=0.749). Conclusion: The Schirmer test, BUT test, and OSDI score were lower in patients with diabetic foot, but they were not statistically significant. In future studies, peripheral neuropathy examination and corneal confocal microscopy may be beneficial when evaluating dry eye parameters in this group of patients.
有糖尿病足和无糖尿病足的糖尿病患者干眼症检查结果比较
目的:比较有糖尿病足和无糖尿病足的糖尿病患者的干眼症检查结果。 方法:将患有糖尿病足和未患有糖尿病足的糖尿病患者纳入这项横断面对照研究:有糖尿病足和无糖尿病足的糖尿病患者均被纳入这项横断面对照研究。记录每位受试者的泪液破裂时间(BUT)和施尔默试验结果。对每位受试者进行眼表疾病指数(OSDI)问卷调查。 结果研究中共有 48 名糖尿病患者,其中半数患有糖尿病足(24 人)。有糖尿病足和没有糖尿病足的患者在年龄和性别分布上相似。糖尿病足患者的 BUT 中位数(右眼 4.0 [3.0 - 6.0] 秒,左眼 4.5 [3.0 - 6.5] 秒)(无糖尿病足患者的 BUT 中位数(右眼 4.0 [3.8 - 6.2] 秒,左眼 5.0 [3.8 - 5.2] 秒)和 Schirmer 测试(7.0 [5.0 - 17.0] mm,糖尿病足患者左眼为 11.0 [6.8 - 17.0] mm)(无糖尿病足患者右眼为 11.0 [7.0 - 15.8] mm,左眼为 14.5 [6.5 - 18.5] mm)在两组患者中相似。糖尿病足患者(22.7 [13.5 - 36.2])和无糖尿病足患者(28.4 [13.6 - 41.5])的 OSDI 评分相似(P=0.749)。 结论糖尿病足患者的 Schirmer 试验、BUT 试验和 OSDI 评分均较低,但无统计学意义。在今后的研究中,外周神经病变检查和角膜共聚焦显微镜可能有助于评估这类患者的干眼参数。
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