An insight into the ethnopharmacological importance of Indian subcontinent medicinal plant species of Rubiaceae family

IF 1.8 Q3 PHARMACOLOGY & PHARMACY
Debajyoti Roy, Seema Brar, Rohit Bhatia, Naresh Kumar Rangra
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引用次数: 0

Abstract

The 611 genera and over 13,100 species that make up the vast family Rubiaceae are primarily found in tropical and warm climates. These species are utilized in the Indian subcontinent as traditional medicines to treat a number of ailments in addition to their decorative properties. It is proof that species like Adina cordifolia, Anthocephalus cadamba, Cinchona officinalis, Coffea arabica, Morinda citrifolia, and Paederia foetida have received a lot of attention; yet, many phytochemicals should still be undiscovered as none of these species have been carefully examined for their phytochemical composition. This review aims to highlight the traditional, pharmacological, botanical, and phytochemistry aspects of medicinal plant species belonging to the Rubiaceae family. The most significant research findings from the last few decades found in books and online databases like SciFinder and Google Scholar are reported in the paper. So far, more than 100 structurally diverse compounds have been identified from the Rubiaceae family, mainly including alkaloids, glycosides, flavonoids, triterpenoids, phenols, and volatile components. The crude extracts and compounds from the Rubiaceae family have been reported to possess broad pharmacological effects including antimalarial, antibacterial, antihypertension, antidiabetic, antioxidant, and anti-inflammatory effects during biological screening using leads provided by traditional healers. However, there is a dearth of research on the discovery of active phytoconstituents that are in charge of the pharmacological actions indicated above. This provides the researcher with a fresh perspective on how to study this family.

Graphical abstract

Abstract Image

深入了解印度次大陆茜草科药用植物的民族药理学重要性
茜草科有 611 属、13100 多个品种,主要分布在热带和温暖气候地区。在印度次大陆,这些物种除了具有装饰作用外,还被用作治疗多种疾病的传统药物。事实证明,Adina cordifolia、Anthocephalus cadamba、Cinchona officinalis、Coffea arabica、Morinda citrifolia 和 Paederia foetida 等物种受到了广泛关注;然而,由于这些物种的植物化学成分均未经过仔细研究,因此许多植物化学成分仍未被发现。本综述旨在强调茜草科药用植物物种的传统、药理学、植物学和植物化学方面。文中报告了过去几十年中在书籍和在线数据库(如 SciFinder 和 Google Scholar)中发现的最重要的研究成果。迄今为止,已从茜草科植物中鉴定出 100 多种结构不同的化合物,主要包括生物碱、苷类、黄酮类、三萜类、酚类和挥发性成分。据报道,茜草科植物的粗提取物和化合物具有广泛的药理作用,包括抗疟、抗菌、抗高血压、抗糖尿病、抗氧化和抗炎。然而,关于发现具有上述药理作用的活性植物成分的研究却十分匮乏。这为研究人员提供了一个研究该家族的全新视角。
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来源期刊
Advances in Traditional Medicine
Advances in Traditional Medicine PHARMACOLOGY & PHARMACY-
CiteScore
4.30
自引率
0.00%
发文量
50
期刊介绍: Advances in Traditional Medicine (ADTM) is an international and peer-reviewed journal and publishes a variety of articles including original researches, reviews, short communications, and case-reports. ADTM aims to bridging the gap between Traditional knowledge and medical advances. The journal focuses on publishing valid, relevant, and rigorous experimental research and clinical applications of Traditidnal Medicine as well as medical classics. At the same time, the journal is devoted to communication among basic researcher and medical clinician interested in the advancement of Traditional Medicine. Topics covered by the journal are: Medical Classics & History; Biomedical Research; Pharmacology & Toxicology of Natural Products; Acupuncture & Moxibustion; Sasang Constitutional Medicine; Diagnostics and Instrumental Development; Clinical Research. ADTM is published four times yearly. The publication date of this journal is 30th March, June, September, and December.
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