{"title":"An insight into the ethnopharmacological importance of Indian subcontinent medicinal plant species of Rubiaceae family","authors":"Debajyoti Roy, Seema Brar, Rohit Bhatia, Naresh Kumar Rangra","doi":"10.1007/s13596-023-00714-1","DOIUrl":null,"url":null,"abstract":"<div><p>The 611 genera and over 13,100 species that make up the vast family Rubiaceae are primarily found in tropical and warm climates. These species are utilized in the Indian subcontinent as traditional medicines to treat a number of ailments in addition to their decorative properties. It is proof that species like <i>Adina cordifolia</i>, <i>Anthocephalus cadamba</i>, <i>Cinchona officinalis</i>, <i>Coffea arabica, Morinda citrifolia,</i> and <i>Paederia foetida</i> have received a lot of attention; yet, many phytochemicals should still be undiscovered as none of these species have been carefully examined for their phytochemical composition. This review aims to highlight the traditional, pharmacological, botanical, and phytochemistry aspects of medicinal plant species belonging to the Rubiaceae family. The most significant research findings from the last few decades found in books and online databases like SciFinder and Google Scholar are reported in the paper. So far, more than 100 structurally diverse compounds have been identified from the Rubiaceae family, mainly including alkaloids, glycosides, flavonoids, triterpenoids, phenols, and volatile components. The crude extracts and compounds from the Rubiaceae family have been reported to possess broad pharmacological effects including antimalarial, antibacterial, antihypertension, antidiabetic, antioxidant, and anti-inflammatory effects during biological screening using leads provided by traditional healers. However, there is a dearth of research on the discovery of active phytoconstituents that are in charge of the pharmacological actions indicated above. This provides the researcher with a fresh perspective on how to study this family.</p><h3>Graphical abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7613,"journal":{"name":"Advances in Traditional Medicine","volume":null,"pages":null},"PeriodicalIF":1.8000,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Traditional Medicine","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1007/s13596-023-00714-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
The 611 genera and over 13,100 species that make up the vast family Rubiaceae are primarily found in tropical and warm climates. These species are utilized in the Indian subcontinent as traditional medicines to treat a number of ailments in addition to their decorative properties. It is proof that species like Adina cordifolia, Anthocephalus cadamba, Cinchona officinalis, Coffea arabica, Morinda citrifolia, and Paederia foetida have received a lot of attention; yet, many phytochemicals should still be undiscovered as none of these species have been carefully examined for their phytochemical composition. This review aims to highlight the traditional, pharmacological, botanical, and phytochemistry aspects of medicinal plant species belonging to the Rubiaceae family. The most significant research findings from the last few decades found in books and online databases like SciFinder and Google Scholar are reported in the paper. So far, more than 100 structurally diverse compounds have been identified from the Rubiaceae family, mainly including alkaloids, glycosides, flavonoids, triterpenoids, phenols, and volatile components. The crude extracts and compounds from the Rubiaceae family have been reported to possess broad pharmacological effects including antimalarial, antibacterial, antihypertension, antidiabetic, antioxidant, and anti-inflammatory effects during biological screening using leads provided by traditional healers. However, there is a dearth of research on the discovery of active phytoconstituents that are in charge of the pharmacological actions indicated above. This provides the researcher with a fresh perspective on how to study this family.
期刊介绍:
Advances in Traditional Medicine (ADTM) is an international and peer-reviewed journal and publishes a variety of articles including original researches, reviews, short communications, and case-reports. ADTM aims to bridging the gap between Traditional knowledge and medical advances. The journal focuses on publishing valid, relevant, and rigorous experimental research and clinical applications of Traditidnal Medicine as well as medical classics. At the same time, the journal is devoted to communication among basic researcher and medical clinician interested in the advancement of Traditional Medicine. Topics covered by the journal are: Medical Classics & History; Biomedical Research; Pharmacology & Toxicology of Natural Products; Acupuncture & Moxibustion; Sasang Constitutional Medicine; Diagnostics and Instrumental Development; Clinical Research. ADTM is published four times yearly. The publication date of this journal is 30th March, June, September, and December.