Overview of Neutrophil Lymphocyte Ratio (NLR) Based on The Length of Treatment by Pulmonary Tuberculosis Patients in Jambi City

Abstract

Background: Pulmonary tuberculosis (pulmonary TB) is still a global public health problem in the world. Pulmonary TB is a chronic caused by the bacterium Mycobacterium tuberculosis (M.TB). Most TB bacteria are often found infecting the lung parenchyma. Infection due to pulmonary TB disease causes an active immune system in the body which is characterized by an increase in the number of neutrophils (neutrophilia). This infection also causes a decrease in the number of lymphocytes (lymphocytopenia). This study aims to determine the picture of NLR examination results based on the length of treatment undertaken by pulmonary TB patients in Jambi City. Method: The study used descriptive methods with convinience sampling technique. The samples of this study were 40 Pulmonary TB patients from several health centers in Jambi City including the Simpang IV sipin health center, Pakuan baru, Simpang kawat, Rawasari, and Putri ayu. NLR examination in blood was carried out in February-June 2023 at the Hematology Laboratory, majoring in Medical Laboratory Technology using a Hematology analyzer. Result: The results showed the average number of NLR in pulmonary TB patients with a treatment duration of ≤ 2 months, which is 3.68 and in patients with a treatment duration of > 2 months the average was 2.41, p value = 0.023. Conclusion: it can be concluded that the average number of NLR was greatest in pulmonary TB patients with treatment duration ≤ 2 months.