Formulation and Evaluation of Avocado Leaf Extract (Persea americana Mill.) Cream Based on Variations Stearic Acid Concentration

Bahariyan Ramdhan, Anna L Yusuf
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Abstract

Avocado leaves (Persea americana Mill.) contain flavonoid compounds as high as 8.11 mg, so they have potential in the acne healing process. The aim of this research is to create a formulation and evaluate an avocado leaf extract cream preparation. The method used is experimental. Avocado leaf extract cream preparations are made based on varying stearic acid concentrations of 5%, 10% and 15%. Evaluation of the preparation includes organoleptic tests, homogeneity tests, pH tests, spreadability tests, adhesion tests, and viscosity tests. Based on the organoleptic evaluation, the results showed that FI was slightly runny and contained bubbles, FII was slightly thick and FIII was thick. The FI color is brownish white, FII is yellowish white, and FIII is white, and all formulations have a characteristic creamy odor. The homogeneity test shows that all formulas have the same homogeneous preparation. The pH test of the cream preparation showed the same pH value, namely 6. The spreadability test resulted in good spreadability of the cream, namely between 5 and 6.8 cm. The cream adhesion test has an adhesion between 00.53 and 1.38 seconds. And finally, the viscosity test has a viscosity value between 4500 and 8900 mpa. According to the results of this research, avocado leaf extract cream can be used as a cream preparation, with the best stearic acid concentration being 15%.
基于硬脂酸浓度变化的牛油果叶提取物(Persea americana Mill.)
牛油果叶(Persea americana Mill.)含有高达 8.11 毫克的类黄酮化合物,因此具有治疗痤疮的潜力。本研究的目的是创建一种配方,并对牛油果叶提取物乳霜制剂进行评估。采用的方法是实验法。牛油果叶提取物乳霜制剂的硬脂酸浓度分别为 5%、10% 和 15%。制剂的评估包括感官测试、均匀性测试、pH 值测试、涂抹性测试、粘附性测试和粘度测试。感官评价结果表明,FI 稍微流动并含有气泡,FII 稍微粘稠,FIII 粘稠。FI 的颜色为棕白色,FII 为黄白色,FIII 为白色,所有配方都有一种特有的乳白色气味。均一性测试表明,所有配方的制剂均具有相同的均一性。乳霜制剂的 pH 值测试显示出相同的 pH 值,即 6。涂抹性测试结果显示乳霜的涂抹性良好,即在 5 至 6.8 厘米之间。膏霜粘附性测试的粘附性介于 00.53 秒和 1.38 秒之间。最后,粘度测试的粘度值在 4500 至 8900 兆帕之间。根据这项研究的结果,牛油果叶提取物膏霜可用作膏霜制剂,最佳硬脂酸浓度为 15%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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