Intra-operative tranexamic acid: A standard of care?

IF 2.8 3区 医学 Q1 ANESTHESIOLOGY
Nicole Relke , Grace H. Tang , Michelle Sholzberg
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引用次数: 0

Abstract

Peri-operative bleeding is a major cause of morbidity and mortality in patients undergoing surgery. Tranexamic acid, an antifibrinolytic agent, is effective for prevention and treatment of bleeding in a variety of different surgical populations. This review summarizes the evidence supporting the use of tranexamic acid in major surgical settings including cardiac surgery, obstetrics, orthopedic surgery, and non-cardiac surgery. We discuss potential adverse effects with use of tranexamic acid including the theoretical risk of thrombosis. Lastly, we discuss other potential benefits of tranexamic acid including prevention of infection and maintenance of blood-brain barrier integrity.
术中使用氨甲环酸:护理标准?
围手术期出血是手术患者发病和死亡的主要原因。氨甲环酸是一种抗纤溶剂,可有效预防和治疗各种不同手术人群的出血。本综述总结了支持氨甲环酸在心脏外科、产科、骨科和非心脏外科等主要外科手术中使用的证据。我们讨论了使用氨甲环酸的潜在不良反应,包括血栓形成的理论风险。最后,我们讨论了氨甲环酸的其他潜在益处,包括预防感染和维持血脑屏障的完整性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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37
审稿时长
36 days
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