Geographical Variations in Liver Cancer Epidemiology and Diagnosis in the Damietta Governorate, Egypt: An Observational Study

EAS Journal of Biotechnology and Genetics Pub Date : 2023-12-24 DOI:10.36349/easjbg.2023.v05i05.001

Rana R. El Sadda, Heba O. El Sharawy, Omnia H. Gohar, Elhossein A. Moawed, Wael S. El– Tohamy

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Abstract

Background: Liver cancer is a major health problem in Egypt. Understanding its epidemiology can help identify high-risk groups and inform prevention strategies. Objective: To investigate regional and occupational variations in liver cancer characteristics and diagnoses in Damietta governorate, Egypt. Methods: An observational study was conducted using data from the Damietta Cancer Institute in 2021. 128 case diagnosed as Liver cancer were analyzed based on age, location, occupation, cancer stage, provisional diagnosis, and sex. Results: Primary liver cancer was more prevalent in younger individuals while metastatic cancer dominated in older age groups. Certain areas exhibited higher primary cancer rates than others. Provisional diagnoses varied by occupation and location. Male patients presented with more advanced stages and distant metastasis compared to females. Conclusions: Geographical and occupational disparities exist in liver cancer profiles. Sex differences were observed in disease presentation. Robust studies are needed to establish causal relationships and explore underlying disease mechanisms. Understanding regional cancer patterns can help prioritize preventive efforts and develop targeted screening programs.

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埃及达米埃塔省肝癌流行病学和诊断的地域差异：观察研究

背景：肝癌是埃及的主要健康问题：肝癌是埃及的一个主要健康问题。了解其流行病学有助于确定高危人群，并为预防策略提供依据。目的：调查达米埃特地区肝癌特征和诊断的地区和职业差异：调查埃及达米埃塔省肝癌特征和诊断的地区和职业差异。方法：采用数据进行观察研究：利用达米埃塔癌症研究所 2021 年的数据开展了一项观察性研究。根据年龄、地点、职业、癌症分期、临时诊断和性别对 128 例诊断为肝癌的病例进行了分析。结果显示原发性肝癌在年轻人中更为普遍，而转移性肝癌则主要发生在老年人群中。某些地区的原发性癌症发病率高于其他地区。临时诊断因职业和地点而异。与女性相比，男性患者的晚期和远处转移更多。结论：肝癌的发病情况存在地域和职业差异。在疾病的表现方面也存在性别差异。需要进行大量研究，以确定因果关系并探索潜在的疾病机制。了解地区癌症模式有助于确定预防工作的优先次序，并制定有针对性的筛查计划。

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EAS Journal of Biotechnology and Genetics

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