Effects of diclofenac sodium gel phonophoresis in sports activities induced grade-l ankle sprain

Anshika Singh, S. Raghav, Latika Gulyani, Gunjan Chaudhary, Anirudh Srivastava
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Abstract

Purpose: the purpose of this study was to evaluate the effect of diclofenac sodium gel phonophoresis in grade -l ankle sprain. Materials & Methods: 54 patients were randomly included in this study and allocated equally into two groups. Group-1 was managed with therapeutic ultrasound (digital ultrasound machine, a product of HMS marketed in India with frequency of 1 MHz and 3MHz) with diclofenac sodium gel and group-2 was managed with therapeutic ultrasound with aquasonic gel. Therapeutic ultrasound with diclofenac sodium gel, marketed under the name of Voltaren, was administered at a frequency of 1MHz, an intensity of 0.8 W/cm2 with continuous mode (1:1) for five times a week for 2 weeks. The patients were examined by using Numeric Pain Rating Scale (NPRS) and Foot and Ankle Disability Index (FADI). They were assessed on the baseline, after 1st week, and after 2nd week of treatment. Results: one way ANOVA test was used to determine the significant difference at the 0.05 level of significance. There was reduction in NPRS and FADI p-value 0.000 after 2nd week of treatment in group-1 and group-2. But on the basis of mean difference score of NPRS and FADI, group-1 was better effective in terms of reduction of pain and improvement of function periodical manner (Table 3). Conclusion: significant dose-dependently relief was observed in NPRS and FADI for pain in disability for each group treated with diclofenac sodium gel compared with aquasonic gel using ultrasound. Acoustic streaming increased these benefits significantly when used after topical application of diclofenac sodium gel, and the dose-dependent effects of diclofenac sodium gel using therapeutic ultrasound.
双氯芬酸钠凝胶声波透入疗法对体育活动引起的一级踝关节扭伤的影响
目的:本研究旨在评估双氯芬酸钠凝胶音波透入疗法对一级踝关节扭伤的疗效。材料与方法:54 名患者被随机纳入本研究,并平均分配为两组。第一组使用双氯芬酸钠凝胶进行超声波治疗(数字超声波机,HMS 在印度销售的产品,频率为 1 MHz 和 3MHz),第二组使用水声凝胶进行超声波治疗。使用双氯芬酸钠凝胶进行超声波治疗,该凝胶在市场上的名称为 Voltaren,频率为 1MHz,强度为 0.8 W/cm2,采用连续模式(1:1),每周 5 次,持续 2 周。采用数字疼痛评分量表(NPRS)和足踝残疾指数(FADI)对患者进行检查。分别在基线、治疗第一周和第二周后进行评估。结果:在 0.05 的显著性水平下,采用单向方差分析确定显著差异。治疗第二周后,第一组和第二组的 NPRS 和 FADI 下降,P 值为 0.000。但从 NPRS 和 FADI 的平均差异得分来看,第 1 组在减轻疼痛和改善功能方面的疗效更好(表 3)。结论:与使用超声波的水声凝胶相比,使用双氯芬酸钠凝胶治疗的各组在残疾疼痛的 NPRS 和 FADI 中均观察到明显的剂量依赖性缓解。在局部应用双氯芬酸钠凝胶后使用声流疗法可显著增加这些益处,使用治疗性超声波的双氯芬酸钠凝胶的效果与剂量有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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