The Status of B Vitamin in Saudi Adults: A Review

Abeer M. Aljaadi, Fahdah F. Alsunaid, Maha Abdulrahim, Najlaa H. Almehmadi, A. Alzaben
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Abstract

Background and Objective: B vitamins are essential for maintaining several body functions. Assessing micronutrient status in a population is crucial for evaluating the individual or the population’s levels of nutrient sufficiency, deficiency, or toxicity; examining the relationship between a nutrient’s status and adverse health outcomes; and determining nutrient needs to establish reference values. There is lack of periodical national surveys in Saudi Arabia that assess the status of the B vitamins. Therefore, this review summarizes and critique the literature of B vitamin status in Saudi adults age of ≥18 years. Methods and Study Design: Databases (PubMed, Medline and Google Scholar) were searched for articles published between January 1980 to December 2022 using combinations of the terms “Saudi Arabia”, “status”, “level” along with all the corresponding vitamin B keywords and metabolites. Results: Forty three studies were obtained. Only 28 studies were included to the current review. Several studies conducted in Saudi adults measured folate and vitamin B12 status. Fewer studies assessed thiamine, riboflavin, and pyridoxine status. No relevant studies were found on the status of niacin, pantothenic acid, and biotin. Studies on thiamin status have not reported rates of deficiency except for one study reporting a prevalence of 3%. Conflicting findings were observed for riboflavin status, but the most recent evidence suggests a prevalence of 36.9% deficiency among Saudi adults. Folate deficiency appears to be low, whereas vitamin B12 might be of concern among Saudi adults. Conclusions: There were discrepancies in the results of some vitamin status in Saudi adults mainly attributed to differences in biomarkers used, methodologies, regional differences, and/or age group/population.
沙特成年人的 B 族维生素状况:综述
背景和目的:B 族维生素是维持人体多种功能所必需的。评估人群的微量营养素状况对于评价个人或人群的营养素充足、缺乏或毒性水平;研究营养素状况与不良健康后果之间的关系;以及确定营养素需求量以建立参考值至关重要。沙特阿拉伯缺乏定期评估 B 族维生素状况的全国性调查。因此,本综述总结并评论了有关年龄≥18 岁的沙特成年人 B 族维生素状况的文献。方法与研究设计:使用 "沙特阿拉伯"、"状况"、"水平 "以及所有相应的维生素 B 关键字和代谢物组合,检索数据库(PubMed、Medline 和 Google Scholar)中 1980 年 1 月至 2022 年 12 月期间发表的文章。结果:共获得 43 项研究。只有 28 项研究被纳入本次综述。在沙特成年人中进行的几项研究测量了叶酸和维生素 B12 的状况。评估硫胺素、核黄素和吡哆醇状况的研究较少。没有发现关于烟酸、泛酸和生物素状况的相关研究。关于硫胺素状况的研究除一项研究报告了 3% 的缺乏率外,其他研究均未报告缺乏率。关于核黄素状况的研究结果相互矛盾,但最新的证据表明,沙特成年人的缺乏率为 36.9%。叶酸缺乏率似乎较低,而维生素 B12 在沙特成年人中可能值得关注。结论:沙特成年人的某些维生素状况结果存在差异,这主要归因于所使用的生物标志物、方法、地区差异和/或年龄组/人群的不同。
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