The Subcutaneous Variant Dermatofibrosarcoma Protuberans of the Breast With Nipple Areolar Complex Invasion Treated With Central Lumpectomy: A Case Report

Y. Na, Yong Bin Kwon, Sang Yun An, Hye Un Ma, Sang Chun Park, Seorin Jung, Soo Young Lim, Y. Ryu, Hyo Jae Lee, Hyo Soon Lim, Ji Shin Lee, J. Cho, Min Ho Park
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Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare low-grade soft tissue sarcoma and the breast is less commonly affected than the torso. DFSP can be misdiagnosed as neurofibroma, desmoid tumor, malignant melanoma, or Kaposi sarcoma. A variant of DFSP originates from the subcutaneous layer and is called subcutaneous variant dermatofibrosarcoma protuberans (SC-DFSP). It can be easily confused with breast phyllodes tumor, myofibroblastoma, myoepithelioma, or advanced breast cancer, such as fibromatosis-like metastatic carcinoma. Following punch biopsy, the treatment of choice for breast DFSP is complete excision with negative margins ≥ 2 cm. We present a case of breast SC-DFSP with nipple areolar complex invasion.
乳腺皮下变异型原发性皮纤维肉瘤伴乳头乳晕复合体侵犯,采用中央肿块切除术治疗:病例报告
原发性皮肤纤维肉瘤(DFSP)是一种罕见的低级别软组织肉瘤,乳房比躯干较少受累。皮纤维肉瘤可能会被误诊为神经纤维瘤、苔藓样肿瘤、恶性黑色素瘤或卡波西肉瘤。DFSP 的一种变异型起源于皮下层,被称为皮下变异型原发性皮纤维肉瘤(SC-DFSP)。它很容易与乳腺植物瘤、肌纤维母细胞瘤、肌上皮细胞瘤或晚期乳腺癌(如纤维瘤样转移癌)混淆。冲切活检后,乳腺 DFSP 的首选治疗方法是完全切除,阴性边缘≥ 2 厘米。我们报告了一例乳头乳晕复合体受侵的乳腺 SC-DFSP 病例。
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