An Unusual Case of Mixed Superficial and Adenoid Basal Cell Carcinoma in a 57-year-old Filipino Female

Angeli Elaine A Pangilinan
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Abstract

Introduction: Basal cell carcinoma (BCC) is the most common cutaneous malignancy worldwide often occurring in sun-exposed areas. While the nodular variant accounts for the majority of cases, the adenoid type is extremely rare, comprising about 1.3% of all BCCs. Contrary to the typical presentation of BCC, adenoid BCC features a large sized lesion and a tendency to involve non-sun exposed areas such as the trunk. This case study presents a unique form of mixed superficial and adenoid BCC in a 57-year-old Filipino female. Case Report: A 57-year-old female presented with a 2-year history of a slowly enlarging bluish-black plaque with rolled borders on the left flank with noted bleeding, pain, and pruritus. Dermoscopy revealed arborizing vessels, leaf-like structures, blue gray globules, and white streaks, consistent with BCC. Histopathology showed a diagnosis of a superficial and adenoid type of BCC. Conclusion: Encounters with unusual forms of cutaneous carcinoma may arise in dermatologic practice. Dermoscopy serves as a powerful tool in identifying suspicious lesions and a pre-operative biopsy is done to correlate with the clinical diagnosis. Hence, the dermatologist will be able to decide the appropriate treatment option based on the clinical presentation and histopathologic type.
57 岁菲律宾女性混合表皮和腺样基底细胞癌的罕见病例
导言:基底细胞癌(BCC)是全球最常见的皮肤恶性肿瘤,通常发生在阳光暴露的地区。结节型占大多数,腺样型则极为罕见,约占所有 BCC 的 1.3%。与 BCC 的典型表现相反,腺样 BCC 的特点是病变面积大,并倾向于累及躯干等非日光暴露部位。本病例研究介绍了一名 57 岁菲律宾女性的独特表皮和腺样混合型 BCC。病例报告:一名 57 岁的女性患者,因左侧腹部出现边界滚动的蓝黑色斑块并缓慢扩大,伴有出血、疼痛和瘙痒,病史长达 2 年。皮肤镜检查发现树枝状血管、叶状结构、蓝灰色球状物和白色条纹,与 BCC 一致。组织病理学显示,诊断结果为浅表性腺样型 BCC。结论在皮肤科临床实践中,可能会遇到不同寻常的皮肤癌。皮肤镜是识别可疑病变的有力工具,术前活检可与临床诊断相关联。因此,皮肤科医生能够根据临床表现和组织病理学类型决定适当的治疗方案。
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