Development and Analysis of Biomaterial Based on Calcium Sulfate Hemihydrate and Epoxy Resin

Sadia Arshad, Hafsa Aijaz, Muhammad Rizwan, Tooba Khan, Muhammad Zeeshan Ul Haque
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Abstract

Bone deformation and the degradation of the joint are one of the most common problems faced around the world, especially after the age of 50. Materials like Allograft and Polymethyl-Methacrylate (PMMA) are used in traditional orthotics and prosthetics, and for bone grafting/filling procedures, however, these materials can be expensive. This research proposes, the fabrication of a novel material by utilizing Calcium-Sulfate Hemihydrate (CaSO4. 1/2H2O), and epoxy resin, which can be used as a cost-effective orthotic and prosthetic material. The materials are already used as bone adhesives and bone grafts, hence, are compatible and non-toxic. The fabricated composite material possesses physical properties closest to the natural human bone and is also hydrophilic. Samples with different ratios of the constituents were fabricated and tested for their hardness, compression, and contact angle values using a Hardness tester, PASCO compression tester, and Image J software. The hardness test results indicate that sample 1 has the hardness value i.e., 29.5 ± 2.50 HV in contrast the hardness value of a human bone is found to be 33.3
基于半水硫酸钙和环氧树脂的生物材料的开发与分析
骨变形和关节退化是全世界最常见的问题之一,尤其是在 50 岁以后。同种异体移植和聚甲基丙烯酸甲酯(PMMA)等材料被用于传统的矫形器、假肢和骨移植/填充手术中,但这些材料可能价格昂贵。本研究提出利用半水硫酸钙(CaSO4. 1/2H2O)和环氧树脂制造一种新型材料,这种材料可用作具有成本效益的矫形和修复材料。这些材料已被用作骨粘合剂和骨移植材料,因此具有兼容性和无毒性。制成的复合材料具有最接近天然人体骨骼的物理特性,而且还具有亲水性。使用硬度测试仪、PASCO 压缩测试仪和 Image J 软件,制作并测试了不同成分比例的样品的硬度、压缩和接触角值。硬度测试结果表明,样品 1 的硬度值为 29.5 ± 2.50 HV,而人类骨骼的硬度值为 33.3 ± 2.50 HV。
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