The pile-supported embankment has been widely adopted in highway widening projects. There is often significant differential settlement between the new and old embankments. Previous studies have not clarified the interaction mechanisms between different parts of the widening subgrade. In this research, a series of centrifuge model tests were carried out on the subgrades widened by pile-supported embankment on the soft soil base. The effect of the old embankment and piles on the subgrade deformation subject to new embankment is analyzed based on the full-field measurement results of displacement. The embankment displacement is mainly vertically downward and basically caused by the deformation of the soft soil base. The old embankment redistributes the vertical deformation of soft soil base by increasing and decreasing the vertical displacement in turn along the direction towards the slope surface. The piles exhibit supporting effect on the embankment above and restrict the vertical movement of the soil base. The piles influence the deformation of soft soil base within a certain area which expands with the increasing number of piles. The boundary of the pile influential area moves towards the subgrade axis with increasing depth. The vertical deformation of soft soil base shows peaks that are nearly linearly distributed along depth in the pile influential area. As the number of piles increases, the verticality degree of such linear distribution changes from the vertical to the slope firstly and then reverts to the vertical.