Hyperoxidized PRDX3 as a specific ferroptosis marker.

Life metabolism Pub Date : 2023-12-01 Epub Date: 2023-11-18 DOI:10.1093/lifemeta/load042
Yuelong Yan, Boyi Gan
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引用次数: 0

Abstract

The lack of a reliable and specific marker for ferroptosis has hindered the advancement of treatments related to this cell death mechanism toward clinical application. A recent study published in Molecular Cell has identified hyperoxidized peroxiredoxin 3 (PRDX3) as a promising marker for ferroptosis, opening up new avenues for monitoring and targeting ferroptosis in disease treatment.

过氧化的 PRDX3 是一种特异性铁变态反应标记。
由于缺乏可靠而特异的铁中毒标记物,阻碍了与这种细胞死亡机制有关的治疗方法走向临床应用。最近发表在《分子细胞》(Molecular Cell)上的一项研究发现,过氧化过氧还蛋白3(PRDX3)是一种有希望的铁中毒标记物,这为在疾病治疗中监测和靶向铁中毒开辟了新途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
1.10
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