Cerebral infarction caused by Trousseau syndrome associated with cervical cancer.

IF 3.4 2区 医学 Q1 OBSTETRICS & GYNECOLOGY
Journal of Gynecologic Oncology Pub Date : 2024-07-01 Epub Date: 2024-01-01 DOI:10.3802/jgo.2024.35.e41
Motoko Kanno, Mayu Yunokawa, Atsushi Fusegi, Akiko Abe, Hidetaka Nomura, Hiroyuki Kanao
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引用次数: 0

Abstract

Objective: The combination of cancer and hypercoagulable states is often called Trousseau syndrome. In particular, cerebral infarction caused by Trousseau syndrome is reported to have a poor prognosis. In gynecology, there are many reports of ovarian cancer and a few of uterine cancer. Since there has been no comprehensive report of Trousseau syndrome in cervical cancer, we aimed to summarize Trousseau syndrome in cervical cancer.

Methods: Cerebral infarction caused by cancer-related arterial thrombosis was defined as Trousseau syndrome. Patients with cervical cancer diagnosed at our hospital between January 2014 and December 2021 were retrospectively reviewed using the hospital's medical records.

Results: A total of 1,432 patients were included in the study. Trousseau syndrome occurred in 6 patients (0.4%). The mean age of patients with Trousseau syndrome was 63 years (range: 53-78 years). Of the 6 patients who developed Trousseau's syndrome, 4 patients had it before or during initial treatment, and 2 during recurrent/relapsed disease treatment. The 4 patients who developed the syndrome before or during initial treatment had advanced disease: 1 in stage IIIC and 3 in stage IVB. In all cases, the disease was associated with progressive distant metastasis. The median survival time from the onset of Trousseau syndrome was 1 month (range: 0-6 months).

Conclusion: Cervical cancer causes Trousseau syndrome in cases of advanced disease with a short time between the onset of the syndrome and mortality.

与宫颈癌有关的特鲁索综合征导致的脑梗塞。
目的:癌症与高凝状态的结合通常被称为特鲁索综合征。尤其是特鲁索综合征引起的脑梗塞,据报道预后较差。在妇科方面,有许多关于卵巢癌的报道,也有一些关于子宫癌的报道。由于还没有关于宫颈癌特鲁绍综合征的全面报道,我们旨在总结宫颈癌特鲁绍综合征:方法:癌症相关动脉血栓形成导致的脑梗塞被定义为特鲁绍综合征。利用医院病历对 2014 年 1 月至 2021 年 12 月期间在我院确诊的宫颈癌患者进行回顾性研究:结果:共有 1,432 例患者纳入研究。6例患者(0.4%)出现特鲁索综合征。特鲁绍综合征患者的平均年龄为 63 岁(53-78 岁)。在 6 名出现特鲁索综合征的患者中,4 名患者在初始治疗前或治疗期间出现,2 名患者在复发/复治期间出现。在初次治疗前或治疗期间出现特鲁索综合征的 4 名患者均为晚期患者:其中 1 人处于 IIIC 期,3 人处于 IVB 期。所有病例都伴有进展性远处转移。特鲁绍综合征发生后的中位生存时间为 1 个月(0-6 个月):结论:宫颈癌在晚期病例中会导致特鲁绍综合征,且发病与死亡之间的间隔时间较短。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Gynecologic Oncology
Journal of Gynecologic Oncology ONCOLOGY-OBSTETRICS & GYNECOLOGY
CiteScore
6.00
自引率
2.60%
发文量
84
审稿时长
>12 weeks
期刊介绍: The Journal of Gynecologic Oncology (JGO) is an official publication of the Asian Society of Gynecologic Oncology. Abbreviated title is ''J Gynecol Oncol''. It was launched in 1990. The JGO''s aim is to publish the highest quality manuscripts dedicated to the advancement of care of the patients with gynecologic cancer. It is an international peer-reviewed periodical journal that is published bimonthly (January, March, May, July, September, and November). Supplement numbers are at times published. The journal publishes editorials, original and review articles, correspondence, book review, etc.
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