Treating Executive Function in Youth With Attention Deficit Hyperactivity Disorder: A Review of Pharmacological and Non-Pharmacological Interventions.

IF 2.7 3区医学 Q2 PSYCHIATRY

Journal of Attention Disorders Pub Date : 2024-03-01 Epub Date: 2024-01-04 DOI:10.1177/10870547231218925

Timothy E Wilens, Mira Stone, Sylvia Lanni, Amy Berger, Ronan L H Wilson, Melis Lydston, Craig B Surman

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引用次数: 0

Abstract

Introduction: Executive function (EF) deficits are common in youth with ADHD and pose significant functional impairments. The extent and effect of interventions addressing EF in youth with ADHD remain unclear.

Methods: We conducted a systematic literature review using PRISMA guidelines. Included studies were randomized controlled trials of interventions to treat EF in youth with ADHD.

Results: Our search returned 136 studies representing 11,443 study participants. We identified six intervention categories: nonstimulant pharmacological (N = 3,576 participants), neurological (N = 1,935), psychological (N = 2,387), digital (N = 2,416), physiological (N = 680), and combination (N = 366). The bulk of the evidence supported pharmacological interventions as most effective in mitigating EF, followed by psychological and digital interventions.

Conclusion: A breadth of treatments exists for EF in youth with ADHD. Pharmacological, psychotherapeutic, and digital interventions had the most favorable, replicable outcomes. A lack of outcome standardization across studies limited treatment comparison. More data on the persistence of intervention effects are necessary.

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治疗注意力缺陷多动障碍青少年的执行功能：药物和非药物干预综述》。

导言：执行功能（EF）缺陷在患有多动症的青少年中很常见，并造成了严重的功能障碍。针对多动症青少年执行功能的干预措施的范围和效果仍不明确：我们采用 PRISMA 指南进行了系统性文献综述。方法：我们采用 PRISMA 准则进行了系统性文献综述，所纳入的研究均为治疗多动症青少年 EF 的干预措施的随机对照试验：结果：我们搜索到了 136 项研究，涉及 11443 名研究参与者。我们确定了六类干预措施：非刺激性药物疗法（3,576 名参与者）、神经疗法（1,935 名参与者）、心理疗法（2,387 名参与者）、数字疗法（2,416 名参与者）、生理疗法（680 名参与者）和综合疗法（366 名参与者）。大部分证据支持药物干预对减轻 EF 最有效，其次是心理和数字干预：结论：针对多动症青少年的EF存在多种治疗方法。药物、心理治疗和数字化干预的效果最为显著，且可推广。不同研究的结果缺乏标准化，这限制了治疗方法的比较。有必要提供更多有关干预效果持续性的数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Attention Disorders PSYCHIATRY-

CiteScore

7.60

自引率

6.70%

发文量

审稿时长

6-12 weeks

期刊介绍： Journal of Attention Disorders (JAD) focuses on basic and applied science concerning attention and related functions in children, adolescents, and adults. JAD publishes articles on diagnosis, comorbidity, neuropsychological functioning, psychopharmacology, and psychosocial issues. The journal also addresses practice, policy, and theory, as well as review articles, commentaries, in-depth analyses, empirical research articles, and case presentations or program evaluations.